Contralateral neck metastases in lateralised, resectable advanced stage oropharyngeal squamous cell carcinoma—Results of 57 patients undergoing bilateral selective neck dissection

Long‐term swallowing outcomes following transoral surgery and adjuvant radiotherapy vs adjuvant chemoradiotherapy for oropharyngeal carcinoma: Our experience in 37 patients

“…Of particular significance, is that two patients in the adjuvant CRT group did undergo radiotherapy at treatment dose to the contralateral neck due to being pathologically restaged to N2c disease after bilateral selective neck dissections. This potentially confounding variable should be considered when interpreting these results, as bilateral neck irradiation has been linked to worsening swallowing outcomes . During the study period, our practice evolved meaning patients with N2b disease were more likely to undergo bilateral neck dissection in the later years of the study period, intending to avoid bilateral neck irradiation, due to a perceived functional advantage of unilateral radiotherapy .…”

“…This potentially confounding variable should be considered when interpreting these results, as bilateral neck irradiation has been linked to worsening swallowing outcomes. 10 During the study period, our practice evolved meaning patients with N2b disease were more likely to undergo bilateral neck dissection in the later years of the study period, intending to avoid bilateral neck irradiation, due to a perceived functional advantage of unilateral radiotherapy. 10 Whilst the majority of patients in our cohort were treated for T2 tumours, there was a higher proportion of patients with T3 primary tumours in the group receiving However, this did not appear to convey the potential worsened swallowing outcomes in this group as previous data suggest.…”

“…10 During the study period, our practice evolved meaning patients with N2b disease were more likely to undergo bilateral neck dissection in the later years of the study period, intending to avoid bilateral neck irradiation, due to a perceived functional advantage of unilateral radiotherapy. 10 Whilst the majority of patients in our cohort were treated for T2 tumours, there was a higher proportion of patients with T3 primary tumours in the group receiving However, this did not appear to convey the potential worsened swallowing outcomes in this group as previous data suggest. 8 The retrospective nature of this study meant we were unable to capture all patients receiving treatment during the study period so those patients with missing swallowing outcome data were excluded from analysis.…”

Orofarenks Kanserlerinde Boyun Metastazlarına Yaklaşım

“…Bu hastalarda tedavi seçenekleri cerrahi veya radyoterapi olabilir (1,2). İleri nodal hastalıkta (N2veya N3) ise boyun diseksiyonu ve ardından kemoradyoterapi ile kombine tedavi tercih edilebilir (2,9). Özellikle cerrahi sınır pozitifliği ve ekstrakapsüler yayılım varsa kombine kemoradyoterapi göz önünde bulundurulmalıdır.…”

“…Özellikle cerrahi sınır pozitifliği ve ekstrakapsüler yayılım varsa kombine kemoradyoterapi göz önünde bulundurulmalıdır. Eğer ekstrakapsüler yayılım yoksa tek başına radyoterapi ile tedavi edilebilir (9). KAYNAKLAR…”