Contraindications to vasoconstrictors in dentistry: Part III

Comparison of the anaesthetic efficacy of epinephrine concentrations (1 : 80 000 and 1 : 200 000) in 2% lidocaine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a randomized, double‐blind clinical trial

“…However, when multiple injections are administered, the potential for adverse drug reactions increases (Goulet et al . , Perusse et al . ).…”

“…This increased risk may be more significant amongst patients with severe cardiovascular disease or patients taking medications that interact with epinephrine and potentiate adverse drug reactions (Goulet et al . , Perusse et al . ).…”

Takayasu's arteritis: what should the dentist know?

“…This choice was because the child was receiving a nonselective β‐blocker (propranolol) for control of arterial hypertension. The drug has some potential to interact with vasoconstrictors of the group of sympathomimetic amines (adrenaline, noradrenaline) and induce an increase in arterial pressure and secondary reflex bradicardia if injected into a blood vessel [14,15].…”

Perioperative evaluation and management in dermatologic surgery

“…Monoamine oxidase inhibitors can produce hypertension acutely with the administration of epinephrine, and tricyclic antidepressants can produce hypertension, bradycardia, and arrhythmias when given with epinephrine. 24 Anticoagulants are common medications of concern in a preoperative evaluation. An increasingly large number of compounds are being used as anticoagulants, including aspirin, nonsteroidal antiinflammatory drugs, warfarin, vitamin E, clopidogrel, ticlopidine, low moleculareweight heparin, and herbal medications.…”