Contraception in women over 40 years of age

Allen, Rebecca H.; Cwiak, Carrie; Kaunitz, Andrew M.

doi:10.1503/cmaj.121280

Cited by 57 publications

(37 citation statements)

References 80 publications

(88 reference statements)

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“…A previous review showed that 17% of Canadian women more than 40 years of age use oral contraceptives compared with 10% in the UK. 19 In addition, inaccurate estimations of hormone prevalence could have further contributed to the disparity. The UK study obtained prevalence of hormone exposure on current users only, and the past exposures were estimated based on other published studies or were calculated using the difference of current users in population prevalence from one year to the next.…”

Section: Discussionmentioning

confidence: 99%

Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012

Grevers

Grundy

Poirier³

et al. 2016

CMAJ Open

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Background: Hormonal contraceptives and hormone replacement therapies are classified as carcinogenic to humans (group 1) by the International Agency for Research on Cancer. We sought to estimate the proportion and total number of cancers attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012.Methods: Population attributable risks were used to estimate the proportion of attributable cases for each associated cancer site. Relative risk estimates were obtained from the most relevant and recent epidemiologic literature. Prevalences of the use of oral contraceptives and hormone therapy in Alberta were collected from Alberta's Tomorrow Project. Specific cancer incidence data were obtained from the Alberta Cancer Registry for the year 2012.Results: Overall, 6.3% of breast cancers (n = 135) diagnosed in Alberta in 2012 were estimated to be attributable to the use of oral contraceptives, and the exposure potentially prevented about 57.3% of endometrial cancers (n = 276) and 29.1% of ovarian cancers (n = 52). About 15.5% of breast cancers (n = 258) and 8.9% of ovarian cancers (n = 13) were estimated to be attributable to the use of hormone therapy, whereas 11.3% of endometrial cancers (n = 48) were possibly prevented by the exposure.Interpretation: Based on our estimates, oral contraceptive use resulted in a net protective effect among the cancer sites studied, thus reducing the cancer burden in Alberta in 2012. The use of hormone therapy was estimated to increase the cancer burden in the province, therefore the risk and benefit of hormone therapy should be carefully considered before use. Abstract ResearchSee also www.cmajopen.ca/lookup

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Section: Discussionmentioning

confidence: 99%

Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012

Grevers

Grundy

Poirier³

et al. 2016

CMAJ Open

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“…Все это укла-дывается в рамки вышеизложенных проблем пере-ходного периода, поэтому рассмотрение данных во-просов может представить интерес для практическо-го врача [14,15].…”

Section: Modern Approaches To Contraception For Women In Perimenopausunclassified

Modern approaches to contraception for women in perimenopausal period (literature review)

Pestrikova¹,

Yurasova²,

Yurasov³

2016

Probl. reprod.

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Перименопаузальный период -период жизни женщины, характеризующийся естественным воз-растным угасанием функций половой системы. Включает переходный период, менопаузу и 2 года постменопаузального периода [1].Выбор контрацепции в возрасте старше 45 лет, т.е. в так называемом «переходном» периоде, пред-ставляет нередко весьма сложную задачу в силу осо-бенностей этого возрастного периода, связанного с неизбежными процессами постепенного угасания функции яичников, наличием ряда гинекологиче-ских и экстрагенитальных заболеваний, появлением вегетососудистых и других ранних симптомов кли-мактерия. Несмотря на то что в этом возрастном пе-риоде фертильность снижается, случаи рождения детей у женщин старше 45 лет не так уж и редки. По

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“…[7]. В Канаде частота абортов у женщин в воз-расте 40 лет и старше составляет 4,3% от их общего числа; хотя в этой возрастной группе она ниже, чем у молодых женщин (13 на 1000 женщин), но остается достаточно высокой -2,9 на 1000 женщин [8].Таким образом, проблема нежелательной беременности и «поздних» абортов не теряет своей актуальности вследствие морально-этических вопросов и неиз-бежных рисков для матери и новорожденного, если женщина решается ее сохранить.…”

Section: внутриматочная контрацепцияunclassified

LNG-IUS for helping a doctor during the most difficult period of women’s reproductive aging

Yureneva¹,

Ilina²

2016

Probl. reprod.

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Contraception in women over 40 years of age

Cited by 57 publications

References 80 publications

Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012

Cancer incidence attributable to the use of oral contraceptives and hormone therapy in Alberta in 2012

Modern approaches to contraception for women in perimenopausal period (literature review)

LNG-IUS for helping a doctor during the most difficult period of women’s reproductive aging

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