Contour-Based Algorithm for Tracking Cells and Cell-Material Analyses

Abstract

Cellular tracking has been employed complex cell-cell and cell-material interactions roles in tissue development and disease progres often performed manually, however limitation manual tracking make it impractical for populations of cells. To address these lim automated tracking algorithms have been devel these algorithms are incapable of tracking cel events or cell divisions. Here we have deve algorithm in MATLAB that employs a segmentation approach to identify and track c occlusion events. The algorithm further ana during occlusion events using a cost analysis to d mislabeled cells.

Energy barriers and cell migration in densely packed tissues

“…We next augment this simple model to account for an additional feature of single-cell motility: single cells on substrates tend to move along the same direction for long periods of time due to polarization of the mechanical components that generate traction forces. 31,32 This directed motion has been shown to be important in other models for embryonic tissues 11 and occurs in addition to the random uctuations induced by changes to the cell shape that are modeled by 3. Therefore we include directed cell motion in an SGR-like framework.…”