Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review

Abstract

Use of oCP in a continuous fashion following conservative surgery for endometriosis is more beneficial to cyclic use.

Reply to: Continuous versus cyclic oral contraceptives for endometriosis: any conclusive evidence?

“…However, ''estroprogestins'' (which was the main term used in the title of the article by Muzii et al [1] ) is apparently an extremely rare term as it appears in only 15 articles in the Medline database to date (date of search: 3.11.15). Fortunately, the results and conclusions by Muzii et al [3] are in line with the rest of the evidence in the existing literature and inclusion of this study does not significantly alter the conclusions of our systematic review [2].…”

“…We would like to thank Dr Muzii et al [1] for their constructive comments regarding our recent systematic review [2]. Indeed, usage of a wider variety of keywords in our search strategy would have resulted to inclusion of one additional eligible multicenter, prospective, randomized trial performed by the same group of authors [3].…”

Association of endometriosis and breast cancer: mini review of the literature

“…The reflux of endometrial tissue via the fallopian tubes, during menstruation, and the consequent implantation of such tissue in distant places, is the prevailing theory [6]. Although endometriosis is a benign lesion, certain characteristics of it are also noted in malignancies.…”

FSRH Guideline (January 2019, amended October 2023) Combined Hormonal Contraception

“…One systematic review186 showed that after conservative surgery, continuous COC use was associated with a significant reduction in dysmenorrhoea and a longer period before dysmenorrhoea recurred compared with cyclical use. One further RCT187 also reported a reduction in endometriosis-associated pelvic pain, an improvement in sexual activity and quality of life in women on a EE/dienogest continuous regimen compared to a 21/7 regimen.…”