Continuous Transcutaneous Monitoring of Fetal Oxygen Tension During Labour

Hugh, A.; Hugh, R.; Schneider, H.; Rooth, Gösta

doi:10.1111/j.1471-0528.1977.tb16231.x

Cited by 158 publications

(86 citation statements)

References 18 publications

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“…It may be advisable to prevent maternal hypoxaemia with supplemental oxygen. The importance of maintaining good oxygenation was revealed when Huch et al (1977) showed an improvement in foetal transcutaneous oxygen tension when the mother was given supplemental oxygen.…”

Section: Effects Of Remifentanil Analgesia On the Foetus And The Neonatementioning

confidence: 99%

Intravenous patient-controlled analgesia with remifentanil in early labour

Volmanen¹

2011

Acta Anaesthesiologica Scandinavica

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Cover design Raimo Ahonen JUVENES PRINT TAMPERE 2010Volmanen, Petri, Intravenous patient controlled analgesia with remifentanil in early labour. AbstractIn four prospective clinical trials, 114 parturients used intravenous patient-controlled remifentanil analgesia during the 1 st stage of labour. The median effective dose per bolus was ascertained to be 0.4 μg/kg and the pain scores were reduced with this by a median of 2 on a numerical scale (0-10). Compared with nitrous oxide, 15 parturients included in a cross-over study reported a larger reduction in pain scores during remifentanil analgesia (1.5 vs. 0.5, p = 0.001) and better pain relief scores (2.5 vs. 0.5 on a ranked five point scale 0-4, p < 0.001). In a parallel study including 45 parturients, epidural analgesia (EDA, 20 ml bupivacaine 0.625 mg/ml and fentanyl 2 μg/ml) was associated with lower pain scores (5.2 vs. 7.3 with remifentanil, p = 0.004) but variables related to satisfaction with analgesia (pain relief score, proportion of mothers with desire to continue with the given medication and termination of the study due to inadequate pain relief) were similar. A comparison of two methods for timing the remifentanil bolus during the uterine contraction cycle suggested that delaying the bolus does not improve analgesia. A period effect was noted in the cross-over trial with higher pain scores and increased drug consumption during the second study period suggesting acute hyperalgesia.Side effects of remifentanil analgesia included respiratory depression warranting oxygen supplementation in 33% of parturients. Sedation was experienced by the parturients using remifentanil and this was scored as stronger than sedation during nitrous oxide and EDA. The number of parturients with nausea did not increase during remifentanil analgesia. Other maternal side effects included dizziness, a difficulty in visual focusing and itching. Foetal heart rate tracing abnormalities were noted. The incidence of abnormal tracings and decreased UapH were not different, however, from that observed during nitrous oxide or EDA. Apgar scores at 1 and 5 minute indicated no neonatal depression. Keywords

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Section: Effects Of Remifentanil Analgesia On the Foetus And The Neonatementioning

confidence: 99%

Intravenous patient-controlled analgesia with remifentanil in early labour

Volmanen¹

2011

Acta Anaesthesiologica Scandinavica

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“…The demographic characteristics of these patients are given in table I. No patient received any medi- (7)(8)(9)(10) cation, with the exception of oxytocin which when used was infused at a constant rate throughout the evaluation period. The dosage and timing of meperidine administration was determined by the managing obstetrician using standard clinical indicators.…”

Section: Patients and Proceduresmentioning

confidence: 99%

“…Fetal oxygenation was measured continuously by a transcutaneous Ρθ2 (tcPoi) electrode in ten patients in the manner described by HUGH [8].…”

Section: Patients and Proceduresmentioning

confidence: 99%

“…Various drugs have been demonstrated to alter FHR variability [4,12,13,16]. A close approximation of human fetal oxygenation can be measured continuously with the use of a transcutaneous osygen electrode during the active phase of labor [8]. Although HUGH et al [7] have reported a decline in human maternal tcPoi following the administration of 50 or 100 mg meperidine intramuscularly, fetal tcPoi was not measured.…”

Section: Introductionmentioning

confidence: 99%

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Human fetal oxygenation (tcPo₂), heart rate variability and uterine activity following maternal administration of meperidine

Baxi¹,

Petrie²,

James³

1988

Journal of Perinatal Medicine

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“…The technique has mainly been tested in perinatal medicine, but also in adults [7,8,13]. A publication on intrapartum registrations of human fetuses in considerable numbers came in 1977 [6], but other mainly preliminary reports have appeared during the last years [5,12,16]. From studies of newborn infants and adults it is knows that the correlation between intraarterial (Pa0 2 ) and transcutaneous oxygen tension (tcPO 2 ) is high provided the peripheral circulation is adequate.…”

Section: Introductionmentioning

confidence: 99%

Continuous, transcutaneous oxygen tension measurements in experiments with Rhesus monkeys and pregnant ewes

Fall¹,

Johnsson²,

Nilsson³

et al. 1979

Journal of Perinatal Medicine

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Continuous Transcutaneous Monitoring of Fetal Oxygen Tension During Labour

Cited by 158 publications

References 18 publications

Intravenous patient-controlled analgesia with remifentanil in early labour

Intravenous patient-controlled analgesia with remifentanil in early labour

Human fetal oxygenation (tcPo₂), heart rate variability and uterine activity following maternal administration of meperidine

Continuous, transcutaneous oxygen tension measurements in experiments with Rhesus monkeys and pregnant ewes

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Continuous Transcutaneous Monitoring of Fetal Oxygen Tension During Labour

Cited by 158 publications

References 18 publications

Intravenous patient-controlled analgesia with remifentanil in early labour

Intravenous patient-controlled analgesia with remifentanil in early labour

Human fetal oxygenation (tcPo2), heart rate variability and uterine activity following maternal administration of meperidine

Continuous, transcutaneous oxygen tension measurements in experiments with Rhesus monkeys and pregnant ewes

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Human fetal oxygenation (tcPo₂), heart rate variability and uterine activity following maternal administration of meperidine