Continuous Topical Administration of a Petrolatum Formulation by a Novel Disposable Diaper

Odio, Mauricio; O’Connor, Robert J.; Sarbaugh, Frank C.; Baldwin, Sue

doi:10.1159/000018366

Cited by 87 publications

(79 citation statements)

References 6 publications

(7 reference statements)

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“…It has been shown that infants in superabsorbent diapers had significantly less diaper dermatitis than those in conventional disposable and cloth diapers [20, 21]. Moreover, a novel diaper has been developed with continuous topical administration of a petrolatum formulation which is described to reduce the contact irritation problems associated with diaper use [22]. …”

Section: Discussionmentioning

confidence: 99%

Microbiological Aspects of Diaper Dermatitis

Ferrazzini

Kaiser²,

Cheng

et al. 2003

Dermatology

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Background: The microbiological basis of diaper dermatitis is not clearly elucidated, although a better knowledge of microbial colonisation can be of importance with regard to an adequate treatment. Objective: To investigate the relevance of Candida sp. and Staphylococcus aureus colonisation in diaper dermatitis and to determine the correlation between the extent of colonisation and the severity of disease. Methods: Growth of Candida sp. and S. aureus in the perianal, inguinal and oral regions was determined by positive/negative and semi-quantitative analysis in an open, multi-centre (n = 3) study. Forty-eight children with healthy skin and 28 with diaper dermatitis were analysed. The severity of diaper dermatitis was assessed using a total symptoms score. Results: Colonisation by Candida sp. was significantly more frequent in children with diaper dermatitis as compared to those with healthy skin (perianal 75 vs. 19%; inguinal 50 vs. 10%; oral 68 vs. 25%, p < 0.0003), whereas colonisation by S. aureus at the 3 swab locations was not different (p > 0.34). There was a highly significant, positive correlation between severity of disease and extent of Candida sp. colonisation at all swab locations. Conclusions: Limited microbial colonisation in diaper dermatitis is of questionable relevance, but extensive colonisation seems to aggravate the symptoms; therefore, we suggest that semi-quantitative evaluation should be preferred to the positive/negative assessment for a differential diagnosis.

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Section: Discussionmentioning

confidence: 99%

Microbiological Aspects of Diaper Dermatitis

Ferrazzini

Kaiser²,

Cheng

et al. 2003

Dermatology

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“…Esto pone de manifiesto que el uso de pañales desechables no sólo es eficaz, sino también seguro y que, en términos generales, los pañales con materiales absorbentes se asocian con formas clínicas menos graves de dermatitis por pañal que los pañales convencionales y los pañales de tela; 12,14,15 por último, que los cuidadores son capaces de reconocer estas ventajas.…”

Section: Discussionunclassified

“…En general, existen estudios [12][13][14][15][16]18 sobre la eficacia de los pañales para la prevención de dermatitis por pañal, incluso evaluada mediante revisión sistemática, 27 que ponen de manifiesto que los pañales con centro de celulosa son superiores a los de tela; los pañales con materiales absorbentes en gel son superiores a los pañales con centro de celulosa exclusivamente, y que los pañales con liberación de formulaciones por contacto son superiores a aquéllos que no las liberan. El pañal BBTips ® evaluado en el presente estudio pertenece al grupo de liberación por contacto y, a pesar de ser semejante a Huggies UltraConfort ® por pertenecer al grupo de absorbentes con gel, la superioridad global de BBTips ® puede estar en relación con esta diferencia.…”

Section: Discussionunclassified

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Estudio comparativo de eficacia entre dos pañales para la prevención y tratamiento de la dermatitis por pañal

et al. 2016

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310www.actapediatrica.org.mx artículo original Acta Pediatr Mex. 2016 nov;37(6):310-321.Estudio comparativo de eficacia entre dos pañales para la prevención y tratamiento de la dermatitis por pañal ResumenUna meta a alcanzar en los niños que usan pañal es mantener una piel intacta dentro del área cubierta por éste y así evitar la dermatitis por pañal.OBJETIVO: comparar la eficacia de dos tipos de pañal para prevenir o tratar la dermatitis por pañal. MATERIALES Y MÉTODOS:ensayo clínico aleatorizado en lactantes de 6 a 12 meses de edad, con o sin dermatitis por pañal, que utilizaron pañales Huggies UltraConfort ® o BBTips ® . Se investigó la presencia o ausencia de dermatitis por pañal y la evaluación de la eficacia del pañal por el médico y el cuidador. El análisis estadístico incluyó análisis uni-y bivariado.RESULTADOS: en el grupo sin dermatitis por pañal se evaluaron 68 lactantes con edad promedio de 8.54 ± 2.09 meses. Había tenido eventos previos de dermatitis por pañal 72%. Catorce lactantes tuvieron dermatitis por pañal. La comparación entre ambos tipos de pañal demostró que BBTips ® fue más eficaz que Huggies UltraConfort ® . En el grupo con dermatitis por pañal se evaluaron 66 pacientes con edad promedio de 8.65 ± 2.4 meses. Había tenido eventos previos de dermatitis por pañal 88%. A los 15 días se habían resuelto 53% de las dermatitis por pañal y al mes 88%. La comparación entre ambos tipos de pañal no demostró diferencias significativas en la eficacia. CONCLUSIONES: en el aspecto preventivo BBTips® fue superior a Huggies UltraConfort ® . Ambos pañales tuvieron eficacia similar en el tratamiento de la dermatitis por pañal.PALABRAS CLAVE: dermatitis por pañal, prevención, tratamiento. Abstract BACKGROUND: To maintain the integrity of the skin in the area covered by a diaper is a goal in order to avoid the development of diaper dermatitis (DD).

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“…Vaseline known being with moisturising as well as water impermeability properties protect the skin [5,10]. In one study, 0 -18 month old children with diaper dermatit were also treated with zinc oxide/vaseline containing diaper as decreased the ratio and severity of diaper dermatit [19,24,25]. In other study diaper containing vaseline was seen to reduce the severity and redness in the 0 -18 month old children with diaper dermatit [20].…”

Section: Discussionmentioning

confidence: 99%

The effect of protective genital care protocol on preventing diaper dermatit development in 0 - 18 month old children using antibiotics

Baran¹,

Çimen²

2013

OJN

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Diaper dermatit is among the widely seen inflamatory skin diseases in neonatals and small 0 -18 month old children. Control of causative agents as well as providing good genital care may prevent or reduce the risk of the disease. The aim of this study is find out the effect of protective genital care on reducing the diaper dermatit development in 0 -18 months old inpatient 0 -18 month old children who are using antibiotic. The study was conducted as prospective halfexperimetal using control-experimental groups. Our samples comprise of 0 -18 month old children admitted at Dokuz Eylul University Practical and Research Hospital, pediatric clinic between January and May 2009, 41 0 -18 month old children as a control group were not under protective genital care, and 42 0 -18 month old children as an experimental group were under the protecion and using vaseline. The mothers of the experimental group 0 -18 month old children were given education. All 0 -18 month old children were followed-up 3 -7 days and the collected data were evaluated in computer using Pearson's chisquare, Fisher's exact chi-square and Yatest-corrected chi-square tests. The diaper dermatit development ratio was 34.1% in the control group and 7.1% in the experimental group (p < 0.05). The rash disease in most of the control group 0 -18 month old children developed in 2 -3 days earlier than those in experimental group which appeared after the fourth day of study. All the 0 -18 month old children with diaper dermatit in the experimental group were found to be with first grade diaper dermatit while those with diaper dermatit in the control group were found to be with second and third grade diaper dermatit. The Diaper dermatit development ratio between the experiment group who were given the protective genital care and vaseline was meaningfully low in comparison to the control group who were not given any care.And those who acquired diaper dermatit disease among experiment group 0 -18 month old children the disease appeared in late days and was rather mild. As the diaper dermatit was found to be more frequent in 0 -18 month old children on antibiotics, to prevent the occurence of the disease proper protective genital care, vaseline use whenever the diaper is changed and giving education to mothers on the subject concerned is advised.

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Continuous Topical Administration of a Petrolatum Formulation by a Novel Disposable Diaper

Cited by 87 publications

References 6 publications

Microbiological Aspects of Diaper Dermatitis

Microbiological Aspects of Diaper Dermatitis

Estudio comparativo de eficacia entre dos pañales para la prevención y tratamiento de la dermatitis por pañal

The effect of protective genital care protocol on preventing diaper dermatit development in 0 - 18 month old children using antibiotics

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