Continuous subcutaneous insulin infusion versus multiple daily injections for type 1 diabetes

Ross, Lindsey; Neville, Kristen A

doi:10.1111/jpc.14480

Cited by 13 publications

(10 citation statements)

References 22 publications

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“…As dietas restritivas eram a luz no fim do túnel, mesmo sendo radicais e ineficazes. Os pacientes chegavam a ingerir menos de 1000 kcal ao dia, e mesmo assim continuavam tendo os níveis de glicose sanguíneos acima do esperado (Ross & Neville, 2019). Todavia, sua descoberta trouxe uma nova chance de vida a todos os pacientes diagnosticados.…”

Section: Resultados E Discussão Insulina E Sua Descobertaunclassified

100 anos de insulina: como a descoberta do hormônio revolucionou o tratamento de diabetes tipo 1

Freitas

Semeghin

Hirata

2021

RSD

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O ano de 2021 foi marcante para os pacientes diagnosticados com diabetes e para a medicina, pois completou-se os 100 anos de descoberta da insulina exógena. Este medicamento revolucionou a qualidade de vida de milhares de pessoas, além de proporcionar para a medicina e indústria farmacêutica, uma nova perspectiva. Nesse contexto, é importante evidenciar que o diabetes mellitus tipo 1 é uma doença autoimune, onde o próprio organismo ataca as células produtoras de insulina, as células beta pancreáticas, sendo assim, é essencial para esses pacientes a utilização desta substância de forma exógena durante toda a vida. Atualmente, existem diversos tipos de insulinas e tecnologias em constante evolução que visam facilitar a adesão e promover maior bem-estar a essas pessoas. Tendo isso em vista, esta revisão literária tem como objetivo mostrar mais sobre os tipos de diabetes que existem, as possíveis causas, os tratamentos existentes, as consequências da falta de controle da glicose, a descoberta da insulina, as tecnologias e uma breve comparação entre o sistema de saúde brasileiro ao sistema de saúde estadunidense. Utilizando materiais bibliográficos como fonte de pesquisa, esse artigo trata-se de um artigo descritivo sobre o diabetes tipo 1, que visto as estimativas e atuais prevalências, torna-se indispensável a discussão sobre essa doença.

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Section: Resultados E Discussão Insulina E Sua Descobertaunclassified

100 anos de insulina: como a descoberta do hormônio revolucionou o tratamento de diabetes tipo 1

Freitas

Semeghin

Hirata

2021

RSD

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“…Using an insulin pump reduces fear of severe hyperglycemia and diabetic coma [12,13]. Patients using a pump have more flexible possibilities regarding meals, diet, everyday activities, and socialization [14], as the pump supports improved selfmanagement habits [15][16][17]. Some additional nonhealth-related benefits, such as reduced worry about supplies while traveling, can significantly improve patients' QoL as well [12].…”

Section: Introductionmentioning

confidence: 99%

Quantitative and qualitative analysis of the quality of life of Type 1 diabetes patients using insulin pumps and of those receiving multiple daily insulin injections

Tzivian

Sokolovska

Grike

et al. 2022

Health Qual Life Outcomes

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Introduction Insulin pump therapy represents an alternative to multiple daily injections and can improve glycemic control and quality of life (QoL) in Type 1 diabetes mellitus (T1DM) patients. We aimed to explore the differences and factors related to the T1DM-specific QoL of such patients in Latvia. Design and methods A mixed-method cross-sectional study on 87 adult T1DM patients included 20 pump users and 67 users of injections who participated in the quantitative part of the study; 8 pump users and 13 injection users participated in the qualitative part. Patients were invited to participate using a dedicated digital platform. Their QoL and self-management habits were assessed using specially developed questionnaires adapted to Latvian conditions. Multiple logistic regression models were built to investigate the association between social and self-management factors and patients’ QoL. In addition, qualitative analysis of answers was performed. Results Insulin pump users were younger, had higher incomes, and reported higher T1DM expenses than users of multiple daily injections. There were no differences in self-management between the groups; Total QoL differed at the 0.1 significance level. In fully adjusted multiple logistic regression models, the most important factor that increased Total QoL was lower T1DM-related expenses (odds ratio, OR 7.02 [95% confidence interval 1.29; 38.0]). Men and those with more years of living with T1DM had better QoL (OR 9.62 [2.20; 42.1] and OR 1.16 [1.05; 1.29], respectively), but the method of administration was not significantly associated with QoL (OR 7.38 [0.87; 62.9]). Qualitative data supported the results of quantitative analysis. Conclusions QoL was the main reason to use an insulin pump, while the expense was the main reason to avoid the use of it or to stop using it. Reimbursement policies thus should be considered to enable patients to choose the more convenient method for themselves.

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“…Using an insulin pump reduces fear of severe hyperglycemia and diabetic coma [12][13]. Patients using a pump have more exible possibilities regarding meals, diet, everyday activities, and socialization [14], as the pump supports improved self-management habits [15][16][17]. Some additional non-health-related bene ts, such as reduced worry about supplies while traveling, can signi cantly improve patients' QoL as well [12].…”

Section: Introductionmentioning

confidence: 99%

Quantitative And Qualitative Analysis Of The Quality Of Life Of Type 1 Diabetes Patients Using Insulin Pumps And Of Those Receiving Multiple Daily Insulin Injections

Tzivian

Sokolovska

Grike

et al. 2022

Preprint

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Introduction: Insulin pump therapy represents an alternative to multiple daily injections and can improve glycemic control and quality of life (QoL) in Type 1 diabetes mellitus (T1DM) patients. We aimed to explore the differences and factors related to the T1DM-specific QoL of such patients in Latvia.Design and methods: A mixed-method cross-sectional study on 87 adult T1DM patients included 20 pump users and 67 users of injections who participated in the quantitative part of the study; 8 pump users and 13 injection users participated in the qualitative part. Patients were invited to participate using a dedicated digital platform. Their QoL and self-management habits were assessed using specially developed questionnaires adapted to Latvian conditions. Multiple logistic regression models were built to investigate the association between social and self-management factors and patients’ QoL. In addition, qualitative analysis of answers was performed. Results: Insulin pump users were younger, had higher incomes, and reported higher T1DM expenses than users of multiple daily injections. There were no differences in self-management between the groups; Total QoL differed at the 0.1 significance level. In fully adjusted multiple logistic regression models, the most important factor that increased Total QoL was lower T1DM-related expenses (odds ratio, OR = 7.02 [95% confidence interval 1.29; 38.0]). Men and those with more years of living with T1DM had better QoL (OR = 9.62 [2.20; 42.1] and OR = 1.16 [1.05; 1.29], respectively), but the method of administration was not significantly associated with QoL (OR = 7.38 [0.87; 62.9]). Qualitative data supported the results of quantitative analysis. Conclusions: QoL was the main reason to use an insulin pump, while the expense was the main reason to avoid the use of it or to stop using it. Reimbursement policies thus should be considered to enable patients to choose the more convenient method for themselves.

show abstract

Continuous subcutaneous insulin infusion versus multiple daily injections for type 1 diabetes

Cited by 13 publications

References 22 publications

100 anos de insulina: como a descoberta do hormônio revolucionou o tratamento de diabetes tipo 1

100 anos de insulina: como a descoberta do hormônio revolucionou o tratamento de diabetes tipo 1

Quantitative and qualitative analysis of the quality of life of Type 1 diabetes patients using insulin pumps and of those receiving multiple daily insulin injections

Quantitative And Qualitative Analysis Of The Quality Of Life Of Type 1 Diabetes Patients Using Insulin Pumps And Of Those Receiving Multiple Daily Insulin Injections

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