Continuous renal replacement therapy versus furosemide for management of kidney impairment in heart transplant recipients with volume overload

Fakhri, Mohammad; Asadollahi, Shadi; Ahmadi, Zargham Hossein; Rashid-Farokhi, Farin; Boloursaz, Mohammad Reza; Masjedi, Mohammad Reza

doi:10.1093/icvts/ivs492

Cited by 10 publications

(5 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, it is interesting that among patients that survived, the long‐term renal function was similar irrespective of the need of RRT in the postoperative period, which is consistent with previous reports . Actually, previous reports have suggested that an early treatment with RRT in HT recipients has been associated with an improvement in estimated GFR in comparison with furosemide . Thus, we suspect that the kind of renal injury developed by these patients early after the surgery is mainly ischemic, and that an early normalization of renal perfusion pressure is followed by recovery of the renal function.…”

Section: Discussionsupporting

confidence: 88%

Predictors of renal replacement therapy after heart transplantation and its impact on long‐term survival

Ivey‐Miranda

Flores‐Umanzor

Farrero-Torres

et al. 2018

Clinical Transplantation

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 88%

Predictors of renal replacement therapy after heart transplantation and its impact on long‐term survival

Ivey‐Miranda

Flores‐Umanzor

Farrero-Torres

et al. 2018

Clinical Transplantation

View full text Add to dashboard Cite

show abstract

“…[23] With regard to renal replacement therapy the use of furosemide has been applied notably in heart transplant recipients with volume overload. [24] The present study aimed to investigate the effects of fluid removal in the achievement of early fascial closure compared with OA patients treated with sole standard of care (SOC).…”

Section: Introductionmentioning

confidence: 99%

A preliminary prospective study of patients who underwent vacuum-assisted and mesh-mediated fascial traction techniques for open abdomen management with negative fluid therapy

et al. 2019

View full text Add to dashboard Cite

It is unclear whether strategies targeting negative fluid balance are associated with facilitated early fascial closure. The present study investigated the effects of fluid removal therapy on early facial closure of open abdomen patients.A prospective study was conducted in patients who underwent open abdomen management with vacuum-assisted and mesh-mediated fascial traction technique. Therapeutic diuresis with torasemide was applied to cause negative fluid balance in the treatment group. The study and follow-up periods were 7 and 180 days, respectively. The observational indices included the intra-abdominal pressure, the number of days to closure, the type of closure, the septic complications, the duration of ventilation support, the duration of initial hospital stay, and the duration of intensive care unit (ICU) stay.A total of 27 patients were divided into the treatment (16 patients) and control (11 patients) groups. The median intra-abdominal pressure (IAP) of the patients of the control and the treatment groups was significantly lower at day 7 compared with the baseline value (P < .0001). IAP was lower in the treatment group compared with that noted in the control group, following day 4 of the fluid removal therapy (P < .05). The percentage weight loss in the treatment group was between 4.80% and 10.88%. The early closure rates were significantly higher in the treatment group compared with those in the control group (75.0% vs 18.2%, P = .0063).Fluid removal therapy combined with vacuum-assisted and mesh-mediated fascial traction provided a high early fascial closure rate for open abdomen patients.

show abstract

“…Excess bleeding and subsequent transfusion of blood products increase the possibility of right ventricular failure, infection, and rejection rate. 2 Meanwhile, it enhances the length of intensive care unit stay, the length of hospital stay, subsequent renal failure due to right ventricular failure, 3 need to renal replacement therapy, 4 and overall morbidity and mortality. 5 In order to assess major bleeding following cardiac surgery, the platelet dysfunction, coagulation pathway derangements, and fibrinolysis should be taken into consideration after excluding the surgical-related issues.…”

Section: Introductionmentioning

confidence: 99%

Prophylactic Fibrinogen Decreases Postoperative Bleeding but Not Acute Kidney Injury in Patients Undergoing Heart Transplantation

Jahangirifard

Ahmadi

Naghashzadeh

et al. 2017

Clin Appl Thromb Hemost

Self Cite

View full text Add to dashboard Cite

The present study is the premier clinical attempt to scrutinize the practicability of prophylactic fibrinogen infusion in patients undergoing heart transplantation (HT). A total of 67 consecutive patients who had undergone HT between January 2012 and December 2014 were assessed. After exclusion of some patients, 23 patients were given preoperative 2 g fibrinogen concentrate over a period of 15 minutes after the termination of cardiopulmonary bypass pump and complete reversal of heparin, and 30 patients were not given. Some laboratories were measured before general anesthesia and at 6 and 24 hours after surgery. In addition, major adverse events were also evaluated during hospitalization. The mean age of the patients was 39.5 ± 11.4 years, with a predominance of male sex (77.4%). All laboratories at baseline were comparable between groups. The length of hospital stay was longer in the control group compared to the fibrinogen group (20 [16-22] vs 16 [12-19] days; P = .005). There was a trend for patients in the fibrinogen group to have more acute kidney injury (AKI) after surgery (10% vs 30.4%) and less reoperation for bleeding (20% vs 8.7%). The amount of postoperative bleeding was significantly higher in the control group compared to the fibrinogen group ( P < .001). The number of packed red blood cell transfused during 24 hours after surgery was significantly lower in the fibrinogen group ( P < .001). The transfusion of fibrinogen in patients undergoing HT may be associated with reductions in postoperative bleeding, the number of packed red blood cells, and hospital length of stay; however, it may enhance postoperative AKI.

show abstract

Continuous renal replacement therapy versus furosemide for management of kidney impairment in heart transplant recipients with volume overload

Abstract: In this study, continuous renal replacement therapy in heart transplant recipients with reduced kidney function was associated with an improvement in estimated glomerular filtration rate status in comparison with furosemide.

Cited by 10 publications

References 22 publications

Predictors of renal replacement therapy after heart transplantation and its impact on long‐term survival

Predictors of renal replacement therapy after heart transplantation and its impact on long‐term survival

A preliminary prospective study of patients who underwent vacuum-assisted and mesh-mediated fascial traction techniques for open abdomen management with negative fluid therapy

Prophylactic Fibrinogen Decreases Postoperative Bleeding but Not Acute Kidney Injury in Patients Undergoing Heart Transplantation

Contact Info

Product

Resources

About