Continuous regional cerebral blood flow monitoring in the neurosurgical intensive care unit

Lee, Sai-Cheung; Chen, Jyi-Feng; Lee, Shih‐Tseng

doi:10.1016/j.jocn.2004.07.016

Cited by 14 publications

(17 citation statements)

References 24 publications

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“…Mannitol has been used for this purpose since the 1960s [5,6]. In addition to establishing an osmotic gradient across the blood-brain barrier, experimental data indicate that mannitol has rheological effects that contribute to ICP reduction and can affect cerebral blood flow (CBF) both regionally and at the level of the microcirculation [6][7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

“…Studies evaluating the clinical effect of mannitol on blood flow and oxygenation have been inconsistent. Mannitol has been shown to transiently increase CBF in several small studies of patients with a variety of diagnoses, [7][8][9] but this finding could not be confirmed in a group of patients with ICH [12]. Similarly, data regarding the effect of mannitol on cerebral oxygenation in TBI have been conflicting [13][14][15][16].…”

Section: Discussionmentioning

confidence: 99%

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Osmotherapy: Use Among Neurointensivists

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Osmotherapy: Use Among Neurointensivists

et al. 2010

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“…The temperature difference between the two reflects local CBF. [50] As cerebral temperature increases, the temperature difference decreases. In patients with severe TBI, it has been used for assessment of autoregulation and vasoreactivity.…”

Section: Cbf Monitoringmentioning

confidence: 99%

Advances in neuro-monitoring

2013

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Neuromonitoring aims to detect harmful physiologic events, early enough to guide the treatment instituted. Evidences encourage us to implement multimodal monitoring, as no single monitor is capable of providing a complete picture of dynamic cerebral state. This review highlights the role of intracranial pressure monitoring, cerebral oxygenation (jugular venous oximetry, brain tissue oxygenation, near infrared oximetry, cerebral microdialysis) and cerebral blood flow monitoring (direct and indirect methods) in the management of neurologically injured patients. In this context, the recent developments of these monitors along with the relevant clinical implications have been discussed. Nevertheless, the diverse range of data obtained from these monitors needs to be integrated and simplified for the clinician. Hence, the future research should focus on identification of a most useful monitor for integration into multimodal system.

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“…Inadequate blood supply can disrupt neuronal functions and cause irreversible cellular damage [1][2][3]. Hence, monitoring CBF plays an important role in neurosurgical practice.…”

Section: Introductionmentioning

confidence: 99%

Cerebral blood flow sensor with in situ temperature and thermal conductivity compensation

Hartings

et al. 2012

2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS)

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A micromachined blood flow sensor with in situ tissue temperature and thermal conductivity compensation was developed for the continuous and quantitative measurement of intraparenchymal regional cerebral blood flow. The flow sensor operates in a constant-temperature mode and employs a periodic heating and cooling technique. Thermal conductivity compensation is realized by sampling the peak current outputs at the beginning of the heating period and the baseline temperature variation during the heating period is compensated by an integrated temperature sensor. This approach provides highly reliable data with MEMS-based thin film sensors. It achieves sensitivity of 1.467 mV/ml/100gram-min in the linear range from 0 to 160 ml/100gram-min.

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Continuous regional cerebral blood flow monitoring in the neurosurgical intensive care unit

Cited by 14 publications

References 24 publications

Osmotherapy: Use Among Neurointensivists

Osmotherapy: Use Among Neurointensivists

Advances in neuro-monitoring

Cerebral blood flow sensor with in situ temperature and thermal conductivity compensation

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