Continuous monitoring of tissue oxygen tension during hyperoxia and hypoxia

Gottrup, Finn; Gellett, S C; Kirkegaard, L; Hansen, Ebbe Stender; Johannsen, Gunnar

doi:10.1097/00003246-198812000-00011

Cited by 19 publications

(2 citation statements)

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“…The study was conducted under two conditions: breathing room air and receiving an oxygen challenge. Supplemental oxygen has been shown to increase PaO 2 , which in turn increases tissue oxygen tension 8,27–29 . In humans, administering 40–60% (0.4–0.6 FiO 2 ) of oxygen via a facemask with the oxygen flow set at 7–10 L/minute is considered an oxygen challenge.…”

Section: Methodsmentioning

confidence: 99%

How heel oxygenation changes under pressure

Wong¹,

Stotts²,

Hopf³

et al. 2007

Wound Repair Regeneration

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The mechanism of heel pressure ulcers after hip surgery is not entirely understood. The purpose of this one-group, prospective, repeated-measures design study was to examine how the external pressure of the bed surface affects heel skin oxygen tension in adults on the first 3 days after hip surgery. Transcutaneous oxygen sensors were placed on the plantar surface of each foot, close to the heels. Measures were taken on room air and with an oxygen challenge with the heels (1) suspended above the bed surface (preload), (2) on the bed surface for 15 minutes (loading), and (3) again suspended above the bed surface for 15 minutes (unloading). Eighteen hip surgery patients (mean age 58.3+/-16.1 years) from two hospitals participated. When compared with preload on room air, both loading and unloading on all 3 days resulted in a reduction in heel oxygen tension bilaterally (p<0.001). Heel oxygenation decreased without the anticipated hyperemic response, raising the question of whether this is a sign of increased pressure ulcer risk. Further work is needed to understand why this short period of external pressure results in decreased oxygenation and why oxygen tension does not return to baseline when pressure is removed.

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Section: Methodsmentioning

confidence: 99%

How heel oxygenation changes under pressure

Wong¹,

Stotts²,

Hopf³

et al. 2007

Wound Repair Regeneration

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show abstract

“…Paradoxically, in some cases, even multiple organ failure can be improved with the application of extracorporeal support (80,81). Unfortunately, equipment which can measure intracellular pH, pC0 2 and p0 2 and tell the perfusionist quickly about changes at the microvascular level is not yet available for the clinical setting (82). The result is that long-term extracorporeal support becomes trial and error in nature.…”

Section: Future Toolsmentioning

confidence: 99%

Oxygen Pressure field Theory, The Krogh Cylinder and Long-Term Extra corporeal Perfusion: An Old Concept Provides New Insight

Grist,

Meiling

1993

J Extra Corpor Technol

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This article describes oxygen pressure field theory and its relevance to the application of long-term perfusion support. Prolonged applications of extracorporeal support for cardiac or pulmonary failure require a more perceptive understanding of perfusion and how it works over a period of days or weeks. The key to this understanding lies in the concepts of the Krogh tissue cylinder, the lethal corner and perfused capillary density. The interrelationships of these concepts define the microvascular redistribution system and its need to remain in balance in order to maintain homeostasis. An imbalance in any of the aspects described could result in tissue damage and eventual death. Perfusionists attempting to perform long-term extracorporeal support can improve the odds for patient survival with a clear understanding of oxygen pressure field theory and its associated concepts. By maintaining a balance in the microvascular redistribution system, the perfusionist not only keeps the patient alive, but creates an environment where healing can occur over a period of days or weeks.

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Tissue Oxygen Tension Monitoring: Relation to Hemodynamic and Oxygen Transport Variables

Gottrup¹

1991

Update in Intensive Care and Emergency Medicine

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Continuous monitoring of tissue oxygen tension during hyperoxia and hypoxia

Cited by 19 publications

References 0 publications

How heel oxygenation changes under pressure

How heel oxygenation changes under pressure

Oxygen Pressure field Theory, The Krogh Cylinder and Long-Term Extra corporeal Perfusion: An Old Concept Provides New Insight

Tissue Oxygen Tension Monitoring: Relation to Hemodynamic and Oxygen Transport Variables

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