Continuous Monitoring of Mixed Venous Oxygen Saturation in Hemodynamically Unstable Patients

Birman, Harry; Haq, Aminul; Hew, Ernest; Aberman, Arnold

doi:10.1378/chest.86.5.753

Cited by 73 publications

(18 citation statements)

References 5 publications

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“…Monitoring of SvO 2 therefore allows assessment of total tissue oxygen balance and helps the clinician to determine whether CI and oxygen delivery (DO 2 ) are high enough to meet the patient's needs [9,10]. The well-known study by Rivers et al [4] indicated that targeting a mixed central venous oxygen saturation (ScvO 2 ) level greater than 70% during early resuscitation of patients with severe sepsis may improve outcomes.…”

Section: Introductionmentioning

confidence: 99%

High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

Velissaris¹,

Pierrakos²,

Scolletta³

et al. 2011

Critical Care

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Introduction: The aim of this study was to determine whether the degree of fluid responsiveness in critically ill septic patients is related to baseline mixed venous oxygen saturation (SvO 2 ) levels. We also sought to define whether fluid responsiveness would be less likely in the presence of a high SvO 2 (>70%). Methods: This observational study was conducted in a 32-bed university hospital medicosurgical ICU. The hemodynamic response to a fluid challenge was evaluated in 65 critically ill patients with severe sepsis. Patients were divided into two groups (responders and nonresponders) according to their cardiac index (CI) response to the challenge (>10% or <10%). Results: Of the 65 patients, 34 (52%) were fluid responders. Baseline SvO 2 , CI, heart rate (HR) and mean arterial pressure (MAP) were not statistically different between groups. The responders had lower pulmonary artery occlusion pressure (PAOP) and central venous pressure (CVP) at baseline than the nonresponders. After the fluid challenge, there were no differences between the two groups in MAP, CVP, PAOP or HR. There was no correlation between changes in CI or stroke volume index and baseline SvO 2 . Receiver operating characteristic analysis showed that SvO 2 was not a predictor of fluid responsiveness. Conclusions: The response of septic patients to a fluid challenge is independent of baseline SvO 2 . The presence of a high SvO 2 does not necessarily exclude the need for further fluid administration.

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Section: Introductionmentioning

confidence: 99%

High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

Velissaris¹,

Pierrakos²,

Scolletta³

et al. 2011

Critical Care

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“…A stable course for SvO 2 indicates an unchanging relationship between VO 2 and DO 2 ; when used in conjunction with other measures of tissue oxygenation, SvO 2 is relevant for the prognosis and therapy [26][27][28][29][30][31][32][33][34].…”

Section: Discussionmentioning

confidence: 99%

Normal values of SvO 2 as therapeutic goal in patients with multiple injuries

Kremžar

Špec-Marn

Kompan

et al. 1997

Intensive Care Medicine

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“…Mixed venous oxygen saturation (SvO 2 ) measured in the PA is an average of the venous oxygen saturations of the body. It was demonstrated that SvO 2 closely reflects the cardiac output (CO) and tissue oxygen consumption (57,58); thus, an implantable sensor to measure SvO 2 can be used to derive information on CO, which gives an indication of the cardiac status in HF patients.…”

Section: Other Sensor Modalities For Hf Monitoringmentioning

confidence: 99%

Implantable Sensors for Cardiac Function Monitoring

Marcelli

Cercenelli

2013

Wiley Encyclopedia of Electrical and Electronics Engineering

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As heart diseases represent the leading causes of death in the world and the rapidly aging population tends to increase the prevalence of these pathologies, implantable sensors for the continuous monitoring of cardiac function are receiving considerable interest and investment. This article provides an overview of important aspects and challenges dealing with implantable sensor systems for cardiac function monitoring, and it discusses past and recent developments in this area. Part one is a general introduction on design principles for the development of implantable systems, including considerations about the human body's interaction with the implanted device; the appropriate choice of materials, coatings, and packaging techniques ( biocompatibility/biostability ); and concerns about miniaturization and low‐power consumption requirements. Subsequent sections discuss various applications of implantable sensors for cardiac function monitoring, starting from the initial experience of rate‐responsive sensors for cardiac pacing up to focus on sensors, most intensely investigated in the last decade, for monitoring cardiac function alterations secondary to heart failure. A final section is provided about future directions and emerging technologies on implantable sensors for cardiovascular applications. The major challenge for the fulfillment of a successful implantable sensor for cardiac function monitoring deals with demonstrating its clinical effectiveness, along with ensuring its long‐term stability and reliability. To date, many sensors have been investigated, but few of them truly meet these goals and demonstrate their appropriate clinical roles.

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Continuous Monitoring of Mixed Venous Oxygen Saturation in Hemodynamically Unstable Patients

Cited by 73 publications

References 5 publications

High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

Normal values of SvO 2 as therapeutic goal in patients with multiple injuries

Implantable Sensors for Cardiac Function Monitoring

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