Continuous-mode encapsulation of human stem cell spheroids using droplet-based glass-capillary microfluidic device for 3D bioprinting technology

Mesquita, Cássia; Charelli, Letícia Emiliano; Baptista, Leandra Santos; Naveira-Cotta, Carolina P.; Balbino, Tiago Albertini

doi:10.1016/j.bej.2021.108122

Cited by 9 publications

(2 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to the bioink composed of synthetic materials, living cells can also be printed with this technique. For example, the encapsulation of human stem cell spheroids into ALG hydrogels was achievable using droplet-based bioprinters [161]. In this study, cryopreserved human adipose-derived mesenchymal stem cells were thawed and cultured in a flask.…”

Section: Droplet-based Bioprintingmentioning

confidence: 99%

Advances in Three Dimensional Bioprinting for Wound Healing: A Comprehensive Review

Umur,

Bayrak,

Arslan

et al. 2023

Applied Sciences

View full text Add to dashboard Cite

The vulnerability of skin wounds has made efficient wound dressing a challenging issue for decades, seeking to mimic the natural microenvironment of cells to facilitate cell binding, augmentation, and metamorphosis. Many three-dimensional (3D) bioprinted hydrogel-based configurations have been developed using high-tech devices to overcome the limitations of traditional dressing materials. Based on a material perspective, this review examines current state-of-the-art 3D bioprinting for hydrogel-based dressings, including both their advantages and limitations. Accordingly, their potential applications in terms of their performance in vitro and in vivo, as well as their adaptability to clinical settings, were investigated. Moreover, different configurations of 3D bioprinters are discussed. Finally, a roadmap for advancing wound dressings fabricated with 3D bioprinting is presented.

show abstract

Section: Droplet-based Bioprintingmentioning

confidence: 99%

Advances in Three Dimensional Bioprinting for Wound Healing: A Comprehensive Review

Umur,

Bayrak,

Arslan

et al. 2023

Applied Sciences

View full text Add to dashboard Cite

show abstract

“…With the change of the environment, most living organisms in nature tend to evolve with various functional surfaces for survival, thereby realizing the directional and spontaneous transport of droplets. , For example, the anisotropic micro-grooved structure on the rice leaves allows the surface droplets to directionally roll off, which should be derived from the difference in an energy barrier between the longitudinal direction and the horizontal one. , The hierarchical micro/nanostructures on the wings of butterflies motivate the raindrops to fall easily from their body, thereby enabling the wings to dry and allowing for normal flight. , Owing to the wetting gradient force arising from the conical topography, the well-distributed clusters of conical spines and trichomes on the cactus stem accelerate the efficient fog gathering from the hydropenic ambient. − Based on these impressive phenomena, some great efforts have been dedicated to designing a series of functional surfaces to realize self-cleaning, , water-collecting, − microfluidics, − and biomedical detection. , …”

Section: Introductionmentioning

confidence: 99%

Multiple-Droplet Selective Manipulation Enabled by Laser-Textured Hydrophobic Magnetism-Responsive Slanted Micropillar Arrays with an Ultrafast Reconfiguration Rate

Zhang

et al. 2023

Langmuir

View full text Add to dashboard Cite

Biomimetic structures based on the magnetic response have attracted ever-increasing attention in droplet manipulation. Till now, most methods for droplet manipulation by a magnetic response are only applicable to a single droplet. It is still a challenge to achieve on-demand and precise control of multiple droplets (≥2). In this paper, a strategy for on-demand manipulation of multiple droplets based on magnetism-responsive slanted micropillar arrays (MSMAs) is proposed. The Glaco-modified superhydrophobic surface is the basis of multiple-droplet manipulation. The droplet’s motion mode (pinned, unidirectional, and bidirectional) can be readily fine-tuned by changing the volume of droplets and the speed of the magnetic field. The rapid movement of droplets (10–80 mm/s) in the horizontal direction is realized by the unidirectional waves of the micropillar array driven by a specific magnetic field. The bending angle of micropillars can be rapidly and reversibly adjusted from 0 to 90° under the action of a magnetic field. Meanwhile, the liquid-involved light, electric switch, and biomedical detection can be designed by manipulating the droplets on demand. The superiority of MSMAs in multiple-droplet programmable manipulation opens up an avenue for applications in microfluidic and biomedical engineering.

show abstract

Encapsulation of stem cells

Khanmohammadi¹,

Namini²,

Bagher³

et al. 2023

Principles of Biomaterials Encapsulation : Volume Two

View full text Add to dashboard Cite

Continuous-mode encapsulation of human stem cell spheroids using droplet-based glass-capillary microfluidic device for 3D bioprinting technology

Cited by 9 publications

References 19 publications

Advances in Three Dimensional Bioprinting for Wound Healing: A Comprehensive Review

Advances in Three Dimensional Bioprinting for Wound Healing: A Comprehensive Review

Multiple-Droplet Selective Manipulation Enabled by Laser-Textured Hydrophobic Magnetism-Responsive Slanted Micropillar Arrays with an Ultrafast Reconfiguration Rate

Encapsulation of stem cells

Contact Info

Product

Resources

About