Continuous microfluidic platform combining cell lysis and protein extraction for screening overall process conditions
Ricardo Fradique,
Andreia Jardim,
Ana M Azevedo
et al.
Abstract:BACKGROUNDMicrofluidic devices have been increasingly used as tools to accelerate the development of new biomanufacturing methods, given their ability to test a large set of variables in a short amount of time with minimal reagent consumption. However, while being able to expedite a bioprocess design, the modular aspect of these devices has not been systematically explored, with most applications focusing on single unitary operations. This paper explores the modular design of these devices through the developm… Show more
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