A smart office, a particular case of Building Automation, represents a physical environment enriched with sensing, actuation, communication and computation capabilities aiming at acquiring and exploiting knowledge about the environment and its inhabitants. A fundamental goal of the smart offices is to ensure a comfortable working environment as well as adapting to the circumstances related to optimizing specific variables which indicate the safety and energy efficiency of the office, as well as the health and productivity of its occupants.In this position paper, we illustrate a representative system by exploring emerging technologies, which presents a unique set of challenges and opportunities to research a new generation of software control systems, by supporting non-intrusive interfaces, that put the occupants at the center of the system's concerns, by focusing on comfort and well-being while still leveraging the occupants' behaviour.