Continuous, 10-Year Wound Infection Surveillance

Olson, Mary M.; Lee, James T.

doi:10.1001/archsurg.1990.01410180120020

Cited by 238 publications

(28 citation statements)

References 41 publications

(6 reference statements)

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“…SSI rates reported in this study were as follows: 2.1% for clean, 3.3% for clean/contaminated, 6.4% for contaminated, and 7.1% for dirty cases [9]. This corroborated data from a study by Olson and Lee [10] in 1990 that found reduced rates of infection in clean, clean/contaminated, and contaminated procedures compared to rates from 1977.…”

Section: Introductionsupporting

confidence: 88%

The Relationship between Preoperative Wound Classification and Postoperative Infection: A Multi-Institutional Analysis of 15,289 Patients

et al. 2013

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BackgroundDespite advances in surgical techniques, sterile protocols, and perioperative antibiotic regimens, surgical site infections (SSIs) remain a significant problem. We investigated the relationship between wound classification (i.e., clean, clean/contaminated, contaminated, dirty) and SSI rates in plastic surgery.MethodsWe performed a retrospective review of a multi-institutional, surgical outcomes database for all patients undergoing plastic surgery procedures from 2006-2010. Patient demographics, wound classification, and 30-day outcomes were recorded and analyzed by multivariate logistic regression.ResultsA total of 15,289 plastic surgery cases were analyzed. The overall SSI rate was 3.00%, with superficial SSIs occurring at comparable rates across wound classes. There were similar rates of deep SSIs in the clean and clean/contaminated groups (0.64%), while rates reached over 2% in contaminated and dirty cases. Organ/space SSIs occurred in less than 1% of each wound classification. Contaminated and dirty cases were at an increased risk for deep SSIs (odds ratios, 2.81 and 2.74, respectively); however, wound classification did not appear to be a significant predictor of superficial or organ/space SSIs. Clean/contaminated, contaminated, and dirty cases were at increased risk for a postoperative complication, and contaminated and dirty cases also had higher odds of reoperation and 30-day mortality.ConclusionsAnalyzing a multi-center database, we found that wound classification was a significant predictor of overall complications, reoperation, and mortality, but not an adequate predictor of surgical site infections. When comparing infections for a given wound classification, plastic surgery had lower overall rates than the surgical population at large.

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Section: Introductionsupporting

confidence: 88%

The Relationship between Preoperative Wound Classification and Postoperative Infection: A Multi-Institutional Analysis of 15,289 Patients

et al. 2013

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“…23,24 Our data suggest that CIPϩMET therapy provides high rates of clinical and bacteriologic success and may also reduce the incidence of wound infection (11% CIPϩMET vs. 19% PIP/TAZO; P ϭ .04). Because patients with wound infections were considered failures to respond in this study, the lower wound infection rates in the CIPϩMET patients would contribute to the higher clinical success rates found in these patients.…”

Section: Discussionmentioning

confidence: 75%

Comparison of Intravenous/Oral Ciprofloxacin Plus Metronidazole Versus Piperacillin/Tazobactam in the Treatment of Complicated Intraabdominal Infections

et al. 2000

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“…Wound associated infections following cardiac surgery contribute considerably to morbidity and mortality [20, 21]. The estimated SSI risk associated with cardiothoracic procedures is as great as 33% [22].…”

Section: Discussionmentioning

confidence: 99%

Postoperative differences between colonization and infection after pediatric cardiac surgery-a propensity matched analysis

Lex

Cserép

Breuer

et al. 2013

J Cardiothorac Surg

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BackgroundThe objective of this study was to identify the postoperative risk factors associated with the conversion of colonization to postoperative infection in pediatric patients undergoing cardiac surgery.MethodsFollowing approval from the Institutional Review Board, patient demographics, co-morbidities, surgery details, transfusion requirements, inotropic infusions, laboratory parameters and positive microbial results were recorded during the hospital stay, and the patients were divided into two groups: patients with clinical signs of infection and patients with only positive cultures but without infection during the postoperative period. Using propensity scores, 141 patients with infection were matched to 141 patients with positive microbial cultures but without signs of infection. Our database consisted of 1665 consecutive pediatric patients who underwent cardiac surgery between January 2004 and December 2008 at a single center. The association between the patient group with infection and the group with colonization was analyzed after propensity score matching of the perioperative variables.Results179 patients (9.3%) had infection, and 253 patients (15.2%) had colonization. The occurrence of Gram-positive species was significantly greater in the colonization group (p = 0.004). The C-reactive protein levels on the first and second postoperative days were significantly greater in the infection group (p = 0.02 and p = 0.05, respectively). The sum of all the positive cultures obtained during the postoperative period was greater in the infection group compared to the colonization group (p = 0.02). The length of the intensive care unit stay (p < 0.001) was significantly longer in the infection group compared to the control group.ConclusionsBased on our results, we uncovered independent relationships between the conversion of colonization to infection regarding positive S. aureus and bloodstream results, as well as significant differences between the two groups regarding postoperative C-reactive protein levels and white blood cell counts.

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Continuous, 10-Year Wound Infection Surveillance

Cited by 238 publications

References 41 publications

The Relationship between Preoperative Wound Classification and Postoperative Infection: A Multi-Institutional Analysis of 15,289 Patients

The Relationship between Preoperative Wound Classification and Postoperative Infection: A Multi-Institutional Analysis of 15,289 Patients

Comparison of Intravenous/Oral Ciprofloxacin Plus Metronidazole Versus Piperacillin/Tazobactam in the Treatment of Complicated Intraabdominal Infections

Postoperative differences between colonization and infection after pediatric cardiac surgery-a propensity matched analysis

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