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Rural Black Women and Depression: A Contextual AnalysisWe use ecological systems theory to guide our investigation of depression among a sample of 102 married Black mothers residing in the rural South. Using self-report data collected via computerized interviews during home visits, we conduct multivariate regression analyses, exploring the associations between depression and (a) spousal support and conflict, (b) cocaregiver support and conflict, (c) child conduct difficulties, and (d) socioeconomic risk. We hypothesize that each of these variables are associated with mothers' depression scores and that the extent to which these familial variables and depression are associated will vary across socioeconomic contexts. Socioeconomic risk, child conduct difficulties, and conflict with a cocaregiver were associated with women's depression in the full model. The moderational hypotheses were upheld for the variables of spousal support and child conduct difficulty. Spousal support and depression have a strong negative association under conditions of high socioeconomic risk and a nonsignificant relationship when socioeconomic risk is low. The association between child conduct difficulty and depression was exacerbated under high socioeconomic risk.