Continued Excellent Results with the Mini-Gastric Bypass: Six-Year Study in 2,410 Patients

Rutledge, Robert; Walsh, Thomas

doi:10.1381/096089205774512663

Cited by 317 publications

(220 citation statements)

References 19 publications

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“…Obesity and type 2 diabetes mellitus (T2DM) are the most common chronic diseases in developed and developing countries (1, 2) The prevalence of diabetes and obesity are reported at 7.7% (3) and 21.5% in Iranian population (4). As reported by international diabetes federation, globally 80% of humans suffering from T2DM are obese at diagnosis (5).…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Roux-en-Y versus One Anastomosis Gastric Bypass on Remission of Diabetes in Morbid Obesity

Abed

Kabir

Jamshidi

et al. 2017

J Minim Invasive Surg Sci

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Background: Laparoscopic one anastomosis gastric bypass (OAGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB) are common treatments for morbid obese patients who suffer from type 2 diabetes mellitus (T2DM). It has been hypothesized that diabetes may be resolved or improved after bariatric procedures, although the exact effect has not been well established. The present study aimed to compare remission of T2DM after LRYGB versus OAGB in this study. Methods: All diabetic obese patients, aged between 16 to 60, who referred to Hazrat Rasul Akram obesity clinic from April 2010 to March 2013 for LRYGB or OAGB were included in the present study. Pre-operative parameters, including glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), body mass index (BMI), and type of diabetes medication were extracted from database and recorded. Pre-operative and three months postoperative values were then compared between the groups. Results: Out of 95 eligible patients, 50 patients underwent OAGB and 45 patients had LRYGB. The two groups were homogenous in distribution of gender, mean age, weight, BMI, and FPG; however, mean HbA1C was relatively higher in LRYGB group (P = 0.05) than other group, which was non-significant after adjustment. Rate of remission was significantly higher in OAGB group than other group after three months follow-up (64.0 versus 31.1%, respectively) (P = 0.002). Conclusions: In our short-term follow-up, OAGB had a higher rate of remission of T2DM compared to LRYGB, which could be due to different baseline value of HbA1c (before surgery) between two groups. Future research is thus suggested with linger follow-up and randomized study design.

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Section: Introductionmentioning

confidence: 99%

Laparoscopic Roux-en-Y versus One Anastomosis Gastric Bypass on Remission of Diabetes in Morbid Obesity

Abed

Kabir

Jamshidi

et al. 2017

J Minim Invasive Surg Sci

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“…The operative technique was described elsewhere. [7] Prophylactic antibiotics (cefazolin sodium, 2 g, intravenous) were given intravenously at the induction of anesthesia. Low molecular weight heparin, starting the evening before surgery until the end of the 2nd postoperative week, and elastic stockings during hospitalization were used for prophylaxis against thromboembolism.…”

Section: Methodsmentioning

confidence: 99%

Effect of laparoscopic mini-gastric bypass on diabetes in morbidly obese patients

Coşkun¹

2017

Laparosc Endosc Surg Sci

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“…Rutledge [12] reported malnutrition in 1.1% of his comparative studies and systemic reviews. [33][34][35][36] LMGB is effective in achieving weight loss; BMI reduction and EWL range 57-92%, for up to 6 years according to the reviewed literature.…”

Section: Safety-complications Of Laparoscopic Mini-gastric Bypassmentioning

confidence: 99%

“…However, there are concerns about biliary reflux, risk of malignancy, marginal ulcer and reflux esophagitis after LMGB [10][11]. Thousands of LMGB have been performed and efficacy of LMGB on weight loss and remission of T2DM have been reported [12][13][14]. We provide a critical evaluation of LMGB on its weight loss efficacy and remission of T2DM together with the safety profile and complications associated with this operation.…”

Section: Introductionmentioning

confidence: 99%

A Safe and Efficacious Alternative to Roux-en-Y Gastric Bypass for the Treatment of Morbid Obesity and Type 2 Diabetes - One Anastamosis / Mini Gastric Bypass

Tan

Park

Kim

et al. 2016

J Metab Bariatr Surg

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Roux-en-y gastric bypass (RYGB) is currently used to treat obesity and metabolic syndrome. It is however technically challenging with a steep learning curve and long operating times. Laparoscopitc mini-gastric bypass (LMGB) is another surgical method that is acclaimed to achieve similar efficacy and yet safe with acceptable complication rates. We reviewed current literature on LMGB on its efficacy and safety profile. Comprehensive search of available literature using a combination of key words was performed, looking out for efficacy and safety end points. Efficacy end points include excess weight loss, change in body mass index (BMI), resolution of metabolic syndrome or T2DM remission. Safety end points include mortality and morbidity rates, short and long term complications. 18 studies were selected with a total of 9392 patients. Follow up range was from 1 year to 6 years with majority of studies achieving 57%-92% excess weight loss (%EWL) within 1 year. Remission of T2DM rates were mostly more than 84%. Several studies reported better %EWL and T2DM remission when compared to SG and RYGB. Overall mortality rate was 0.152%. Morbidity rates vary from 2.7%-12.5%. Some studies reported lower mortality and complication rates in LMGB when compared to SG and RYGB. In summary, MGB is a safe and effective metabolic-bariatric procedure in treating morbid obesity and T2DM. It should be considered an alternative to standard RYGB. Risk of bile reflux, marginal ulcer and anemia needs to be explained to the patient when counselling for such procedure.

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Continued Excellent Results with the Mini-Gastric Bypass: Six-Year Study in 2,410 Patients

Abstract: Overall, the MGB is very safe initially and in the long-term. It has reliable weight loss and complications similar to other forms of gastric bypass.

Cited by 317 publications

References 19 publications

Laparoscopic Roux-en-Y versus One Anastomosis Gastric Bypass on Remission of Diabetes in Morbid Obesity

Laparoscopic Roux-en-Y versus One Anastomosis Gastric Bypass on Remission of Diabetes in Morbid Obesity

Effect of laparoscopic mini-gastric bypass on diabetes in morbidly obese patients

A Safe and Efficacious Alternative to Roux-en-Y Gastric Bypass for the Treatment of Morbid Obesity and Type 2 Diabetes - One Anastamosis / Mini Gastric Bypass

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