“…The variable composition of esterified estrogens precludes the availability of a valid standard for all batches of tablets. Weber et al (466) solved this problem by using as a standard a sample of the same lot of USP esterified estrogen powder used to prepare the batch of tablets. The automated, analytical procedure employed for the content uniformity test is based on the principle of sulfuric acid-induced fluorescence A G C assay for tablets containing belladonna alkaloids in combination with phenobarbital was developed by Zimmerer and Grady (467).…”