“…Like other hepatic focal lesions: triple-phase liver CT protocol plays an important role in the preliminary diagnosis; On the other hand, percutaneous liver biopsy is necessary not only for the confirmation of the diagnosis but also for the establishment of treatment options like neoadjuvant chemotherapy as in our case. [ 11 ] Many authors recommend upfront surgery without preoperative chemotherapy as long as the tumor is localized, resectable, and away from the major vascular structures by the CT scan criteria. However, the treatment with neoadjuvant chemotherapy can lead to a decrease in the tumor size, minimize further spread or distant metastasis, allow the surgical resection of the primary unresectable tumors, and most important decrease the rate of recurrence.…”