Contemporary updates on bioremediation applications of graphene and its composites

Verma, Nikita; Jujjavarapu, Satya Eswari; Mahapatra, Chinmaya; Mutra, Jagadeesh Kumar Reddy

doi:10.1007/s11356-023-26225-9

Cited by 5 publications

(3 citation statements)

References 73 publications

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“…G has shown great potential in various fields, such as water filtration, advanced electronics, and the creation of composite materials. This is mostly because of its remarkable surface area, impressive mechanical strength, and excellent thermal and electrical conductivity (Obayomi et al, 2022;Verma et al, 2023). The remarkable versatility of G is showcased by its wide range of applications, which hold great potential for driving significant advancements in sustainable solutions and environmentally friendly technologies (Kausar and Ahmad, 2024).…”

Section: How Can Industrial Effluent Treatment Be Enhanced Through Th...mentioning

confidence: 99%

Can bacteria and carbon-based nanomaterials revolutionize nanoremediation strategies for industrial effluents?

de Carvalho Lima,

Souza,

Aguiar

et al. 2024

Front. Nanotechnol.

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In this study, we delved into cutting-edge strategies for the effective management of wastewater, a critical issue exacerbated by industrial pollution and urban expansion. We introduce the use of carbon-based nanomaterials (CBNs), either alone or functionalized with bacteria, as a novel nanobiotechnological solution for urgent nanobioremediation needs. This technique is notable for its exceptional ability to remove various industrial pollutants, including heavy metals, pesticides, textiles, and dyes, emphasizing the pivotal role of CBNs. The development of bionanocomposites through the integration of CBNs with bacteria represents a significant advancement in enhancing bioremediation efforts. In this study, we assessed the potential health and environmental risks associated with CBN usage while offering an in-depth evaluation of the adsorption mechanisms and factors influencing bioremediation effectiveness. Furthermore, the improved efficiency in treating industrial effluents facilitated by bionanocomposites was investigated, and their alignment with circular economy principles through recyclability is discussed. We aimed to provide, a detailed overview of recent advancements, challenges, and prospects for CBNs and bacterial application in sophisticated wastewater treatment, underscoring their vital importance in promoting the environment.

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Section: How Can Industrial Effluent Treatment Be Enhanced Through Th...mentioning

confidence: 99%

Can bacteria and carbon-based nanomaterials revolutionize nanoremediation strategies for industrial effluents?

de Carvalho Lima,

Souza,

Aguiar

et al. 2024

Front. Nanotechnol.

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“…[25] Recently, compounds 8-11 with antioxidant activity against AD have been reported (Figure 2). [26][27][28][29] Due to the diverse and complex pathogenesis of AD, [30] multitarget-directed ligands (MTDLs) with two or more complementary biological activities may produce better results than a single target ligand in the treatment of AD, [31] Based on this theory, a variety of dual-target compounds acting on different causative factors have been developed to treat AD, such as compounds 12-15 (Figure 3). [32][33][34][35] Under the guidance of MTDLs theory, dual-target compounds with AChE inhibitory activity and antioxidant activity for the treatment of AD were designed in this paper, and their design philosophy was as follows: compound 16 (Figure 4) exhibited moderate AChE inhibitory activities in vitro, [36] and molecular docking studies showed that the two amide groups and the attached aromatic ring on the A region of compound 16 produce hydrogen bond as well as π-π stacking with Ser-293 and Trp-286 on the peripheral anionic site (PAS) of AChE.…”

Section: Introductionmentioning

confidence: 99%

Design, Synthesis and Evaluation of 8‐(Piperazin‐1‐yl) Imidazo[1,2‐a]Pyrazine Derivatives as Acetylcholinesterase Inhibitors and Antioxidants

Wei,

Du,

Guo

et al. 2024

ChemistrySelect

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A series of 8‐(piperazin‐1‐yl) imidazo [1,2‐a] pyrazine derivatives were designed and synthesized as acetylcholinesterase inhibitors (AChEIs) and antioxidants for the treatment of Alzheimer's disease (AD). Moreover, the biological evaluation results demonstrated that these synthesized compounds exhibited moderate inhibitory activities toward acetylcholinesterase (AChE) and radical scavenging activities. Among them, the compound with the strongest inhibitory activity against AChE had an IC50 value of 0.55 μM, which was higher than that of galantamine as the reference compound (IC50 value=5.01 μM). The compound with the strongest antioxidant activity had an IC50 value of 57.94 μM, which was lower than that of the ascorbic acid (IC50 value=25.70 μM) as the control drug. Furthermore, the results of molecular docking studies indicated that the compound could simultaneously bind to both catalytic active site (CAS) and peripheral anionic site (PAS) of AChE, which was consistent with the mixed inhibition pattern shown by enzyme kinetic studies. The interaction's stability was also assessed using a conventional atomistic 100 ns dynamics simulation study, which revealed the conformational stability of representative compound in the cavity of the AChE. In addition, the molecular properties of all compounds were predicted online through the SwissADME, and most compounds matched the properties of most orally administered drugs. Based on the biological activity and molecular properties, 8‐(piperazin‐1‐yl) imidazo[1,2‐a] pyrazine derivatives as AChEI were valuable for further development.

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“…Chloroform is a chlorinated organic compound of interest due to its widespread use in many industries, including water purification, pharmaceutical production, and heavy manufacturing [3]. Although chloroform has been historically important in these applications, its health benefits have led to closer scrutiny of its safety.…”

Section: Introductionmentioning

confidence: 99%

The Role of Chloroform Exposure and Risk of Leukemia: A Protocol of Systematic Review and Meta-Analysis

Soleimani,

Sadeghi,

Daraei

et al. 2024

Asian Pac J Envi & Cancer

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Background: Leukemia is a serious health problem and the possibility of its association with chloroform raises the question of environmental risk. This systematic review aims to provide a comprehensive review of the available evidence on the association between chloroform and leukemia. Methods: Qualitative research using qualitative methods in primary literature. Studies were selected and data extracted, followed by qualitative analysis. Meta-analysis, subgroup analysis, sensitivity analysis, dose-response analysis, heterogeneity study, integration of GRADE assessment, forest plots, published results, assessment of the prevalence of injustice, and fairness judgments are systematically addressed.Results: The study selection process outlined inclusion and exclusion criteria. Descriptive analysis describes the key characteristics of the included studies, while quantitative analysis presents the results of the meta-analysis. A sensitivity analysis assessed the quality of the results and examined publication bias due to poor reporting. Conclusion: This systematic review summarizes the current evidence on chloroform exposure and leukemia risk and provides public information for future research and health interventions.

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Contemporary updates on bioremediation applications of graphene and its composites

Cited by 5 publications

References 73 publications

Can bacteria and carbon-based nanomaterials revolutionize nanoremediation strategies for industrial effluents?

Can bacteria and carbon-based nanomaterials revolutionize nanoremediation strategies for industrial effluents?

Design, Synthesis and Evaluation of 8‐(Piperazin‐1‐yl) Imidazo[1,2‐a]Pyrazine Derivatives as Acetylcholinesterase Inhibitors and Antioxidants

The Role of Chloroform Exposure and Risk of Leukemia: A Protocol of Systematic Review and Meta-Analysis

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