Contemporary surgical and technical aspects of transurethral resection of bladder tumor

Ouzaïd, I.; Panthier, F.; Hermieu, Jean-François; Xylinas, Évanguelos

doi:10.21037/tau.2019.01.04

Cited by 14 publications

(12 citation statements)

References 13 publications

(16 reference statements)

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“…Up to 44% of cases of HV are not recognized by community pathologists, further leading to mismanaging the patients [ 15 ]. Indeed, the tissue to analyze may be very small and many artefacts may be present due to repeated coagulation during an often piecemeal resection [ 22 ]. For this reason, over the last years the interest in en bloc resection of bladder tumour (ERBT) is constantly increasing [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Bladder cancer histological variants: which parameters could predict the concordance between transurethral resection of bladder tumor and radical cystectomy specimens?

Mantica

Tappero

Parodi

et al. 2021

Cent european J Urol

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Introduction The concordance rate of bladder cancer (BCa) histological variants (HV) between transurethral resection of bladder tumor (TURBT) and radical cystectomy (RC) is sub-optimal and is unclear which factors may influence it. The aim of this study was to identify factors that may be correlated to a higher TURBT-RC concordance rate. Material and methods Consecutive patients who had undergone RC between 2000 and 2019 at a single Institution with pathological evidence of HV were included. Patients with diagnosis of HV both at RC and at the previous TURBT were enlisted in the TURBT-RC Concordance Group (CG), whereas patients with only evidence of HV at RC in the TURBT-RC Non-Concordance Group (NCG). Surgical factors evaluated were the source of energy (mono- vs bipolar), surgeon’s experience (10 mm represented an independent predictor of concordance [OR 2.95; CI (1.01–8.61); p = 0.048]. Tumor recurrence, focality and dimension, source of energy, surgeon’s experience, performance of re-TURBT and total number of specimens at TURBT did not significantly predict the concordance. Conclusions Longer specimens at TURBT yield a higher chance to detect HV before RC. In this light, improving the quality of bladder resection means improving the management of BCa.

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Section: Discussionmentioning

confidence: 99%

Bladder cancer histological variants: which parameters could predict the concordance between transurethral resection of bladder tumor and radical cystectomy specimens?

Mantica

Tappero

Parodi

et al. 2021

Cent european J Urol

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“…TURBT is the first step of a trimodal therapy. TURBT can be performed either by monopolar or bipolar, en bloc or standard resection [20]. A wider margin of tumor-free urothelium around the lesion is required.…”

Section: Transurethral Resection Of Bladder Tumors (Turbt) Preceding ...mentioning

confidence: 99%

Recommendations for planning and delivery of radical radiotherapy for localized urothelial carcinoma of the bladder

Khalifa

Supiot

Pignot

et al. 2021

Radiotherapy and Oncology

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“…TURBT is standard surgical therapeutic procedures to remove cancer lesions from NMIBC patients (Fig. 4A) [53]. During this process, tumor is initially located to identify its grade through cytoscopy.…”

Section: Transurethral Resection Of Bladder Tumor (Turbt)mentioning

confidence: 99%

Non-Muscular Invasive Bladder Cancer: Re-envisioning Therapeutic Journey from Traditional to Regenerative Interventions

Shih¹,

Chen²,

Chang³

et al. 2021

Aging and disease

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Non-muscular invasive bladder cancer (NMIBC) is one of the most common cancer and major cause of economical and health burden in developed countries. Progression of NMIBC has been characterized as lowgrade (Ta) and high grade (carcinoma in situ and T1). The current surgical intervention for NMIBC includes transurethral resection of bladder tumor; however, its recurrence still remains a challenge. The BCG-based immunotherapy is much effective against low-grade NMIBC. BCG increases the influx of T cells at bladder cancer site and inhibits proliferation of bladder cancer cells. The chemotherapy is another traditional approach to address NMIBC by supplementing BCG. Notwithstanding, these current therapeutic measures possess limited efficacy in controlling NMIBC, and do not provide comprehensive long-term relief. Hence, biomaterials and scaffolds seem an effective medium to deliver therapeutic agents for restructuring bladder post-treatment. The regenerative therapies such as stem cells and PRP have also been explored for possible solution to NMIBC. Based on abovementioned approaches, we have comprehensively analyzed therapeutic journey from traditional to regenerative interventions for the treatment of NMIBC.

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Contemporary surgical and technical aspects of transurethral resection of bladder tumor

Cited by 14 publications

References 13 publications

Bladder cancer histological variants: which parameters could predict the concordance between transurethral resection of bladder tumor and radical cystectomy specimens?

Bladder cancer histological variants: which parameters could predict the concordance between transurethral resection of bladder tumor and radical cystectomy specimens?

Recommendations for planning and delivery of radical radiotherapy for localized urothelial carcinoma of the bladder

Non-Muscular Invasive Bladder Cancer: Re-envisioning Therapeutic Journey from Traditional to Regenerative Interventions

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