Contemporary Pacemaker and Defibrillator Device Therapy

Schoenfeld, Mark H.

doi:10.1161/circulationaha.106.618587

Cited by 40 publications

(2 citation statements)

References 142 publications

(139 reference statements)

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“…27 In addition, clinicians caring for heart failure patients may be reluctant to screen for low ejection fraction and/or to refer otherwise appropriate patients for ICD/CRT-D implantation because of concerns about the potential for adverse clinical consequences from ICDs. 28 …”

Section: Discussionmentioning

confidence: 99%

Geographic Variation in Implantable Cardioverter-Defibrillator Use and Heart Failure Survival

Epstein¹,

Polsky²,

Yang³

et al. 2012

Medical Care

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Background Implantable cardioverter-defibrillators and cardiac resynchronization therapy-defibrillators (ICD/CRT-Ds) are evidence-based preventative treatments for many patients with heart failure (HF), yet large numbers of eligible patients remain untreated. It is uncertain if localities with more frequent ICD/CRT-D use have had better rates of HF survival. Objectives To determine if U.S. Hospital Referral Regions (HRRs) with larger increases in the rate of ICD/CRT-D utilization during 2002–2007 also had commensurate increases in HF survival. Research Design Retrospective cohort. Subjects Medicare beneficiaries age 66–80 non-electively hospitalized for HF from 2002–2007. Measures Each HRR’s annual ICD/CRT-D rate was estimated from the cohort’s Medicare procedure claims. Survival duration was determined from Medicare mortality records. HRR-year-level panel regression models were estimated to assess whether an HRR’s ICD/CRT-D rate predicted HF survival, adjusting for baseline differences in survival across HRRs and secular trends. Results 883,002 HF patients were propensity-score matched within HRR across 2002–2007. Across HRRs, growth in ICD/CRT-D use among such patients varied from 1–12 percentage points. Regression models indicated that a 1 percentage point increase in an HRR’s ICD/CRT-D utilization among hospitalized HF patients was associated with an increase in one-year survival of 0.12% (95% confidence interval[CI] 0.03% to 0.21%, p=0.009) and with a 0.26% increase in HF survival at two years (95% CI 0.14% to 0.37%, p<0.001). Conclusions Localities with greater increases in ICD/CRT-D utilization from 2002 to 2007 also had greater improvements in HF survival. Areas with persistently low ICD/CRT-D use may be good targets for programs designed to increase the evidence-based use of defibrillators.

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Section: Discussionmentioning

confidence: 99%

Geographic Variation in Implantable Cardioverter-Defibrillator Use and Heart Failure Survival

Epstein¹,

Polsky²,

Yang³

et al. 2012

Medical Care

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“…Such devices can be classified into two types: those that exist for long periods of time, typically designed to be permanent; and those that disappear, or resorb, in the body after they provide some useful function. The former includes both simple, passive devices such as artificial joints and pins,1 as well as sophisticated electronic components such as deep brain electrical stimulators,2 cardiac pacemakers3 and programmable drug delivery systems 4. The latter, by contrast, is currently available only in the form of passive elements such as resorbable sutures5, 6 or matrices for drug release,7, 8 degradable intravascular stents9, 10 and resorbable plate‐screw systems 11.…”

Section: Introductionmentioning

confidence: 99%

Materials and Fabrication Processes for Transient and Bioresorbable High‐Performance Electronics

Hwang

Kim

Tao

et al. 2013

Adv Funct Materials

226

269

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Materials and fabrication procedures are described for bioresorbable transistors and simple integrated circuits, in which the key processing steps occur on silicon wafer substrates, in schemes compatible with methods used in conventional microelectronics. The approach relies on an unusual type of silicon on insulator wafer to yield devices that exploit ultrathin sheets of monocrystalline silicon for the semiconductor, thin films of magnesium for the electrodes and interconnects, silicon dioxide and magnesium oxide for the dielectrics, and silk for the substrates. A range of component examples with detailed measurements of their electrical characteristics and dissolution properties illustrate the capabilities. In vivo toxicity tests demonstrate biocompatibility in sub‐dermal implants. The results have significance for broad classes of water‐soluble, “transient” electronic devices.

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ICD Follow‐Up and Troubleshooting

Mansour

Khairy

2014

Cardiac Pacing and ICDs

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Contemporary Pacemaker and Defibrillator Device Therapy

Cited by 40 publications

References 142 publications

Geographic Variation in Implantable Cardioverter-Defibrillator Use and Heart Failure Survival

Geographic Variation in Implantable Cardioverter-Defibrillator Use and Heart Failure Survival

Materials and Fabrication Processes for Transient and Bioresorbable High‐Performance Electronics

ICD Follow‐Up and Troubleshooting

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