Contamination status of persistent organochlorines in human breast milk from Japan: Recent levels and temporal trend

Kunisue, Tatsuya; Muraoka, Masayoshi; Ohtake, Masako; Sudaryanto, Agus; Minh, Nguyen Hung; Ueno, Daisuke; Higaki, Yumi; Ochi, Miyuki; Tsydenova, Oyuna; Kamikawa, Satoko; Tonegi, Tomoyuki; Nakamura, Yumi; Shimomura, Hiroshi; Nagayama, Junya; Tanabe, Shinsuke

doi:10.1016/j.chemosphere.2005.11.010

Cited by 92 publications

(24 citation statements)

References 17 publications

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“…The correlation showed very low r 2 (0.0078 and 0.0614 respectively), the same observed by other authors Minh et al, 2004). Tanabe and Kunisue (2006) considered in their work that the absence of correlations between organochlorine compounds levels and age/parity of the donor mothers living in Asian developing countries cannot be clearly explained. The authors point as a possible reason that most woman in these countries may have many children during her life and the first infant is born at a young age of the mother, the same fact is observed in the mothers participating in the present study.…”

Section: Correlations Between Total Ddt In Breast Milk Vs Age and Vssupporting

confidence: 82%

“…Japanese data contamination of DDT and its metabolites (Kunisue et al, 2006) were lower than the found in the samples collected from Madeira River region for both premipara and multipara mothers. The values of contamination to primipara p,p′-DDT(13 ng/g of lipid), p,p ′-DDD (1.2 ng/g of lipid), and p,p′-DDE (330ng/g of lipid) and for multipara mothers the contamination of p,p′-DDT, p,p′-DDD, and p,p′-DDE were 10, 0.67, and 220 ng/g of lipid respectively.…”

Section: Differences In Total Ddt Concentration Between Primipara Andmentioning

confidence: 57%

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DDT and its metabolites in breast milk from the Madeira River basin in the Amazon, Brazil

et al. 2008

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Until the 1990's the 1,1,1-trichloro-bis-2,2′-(4chlorophenyl) ethane (DDT) was sprayed in the walls of the house in the along the Madeira River basin, Brazilian Amazon, a region well known by its large number of malaria cases. In the 1910, the relate of Oswaldo Cruz about health conditions in Madeira River region describes the presence of malaria in rates ranging until 100% of infected people in some localities. Data available in the literature points to the DDT contamination in fishes captured in Madeira River region. Fish is the major source of dietary protein to this people. DDT tends to accumulate in lipid rich tissues being eliminated by different events, including lactation. Considering the importance of the breast milk to the children feeding, the associated risks of DDT exposure via breast milk intake to children must be assessed. This is the main objective of this work: to analyse the presence of the p,p′-DDT and its metabolites p,p′-DDE and p,p′-DDD in 69 human milk samples and to estimate the intake of DDT and its metabolite in terms of total DDT (total DDT = p,p′-DDE + p,p′-DDD+ p,p′-DDT). All sample showed contamination with DDT and its metabolites ranging from 25.4 to 9361.9 ng of total DDT / g of lipid (median=369.6 ng of total DDT / g of lipid) and 8.7 % of the Estimated Daily Intake (EDI), in terms of total DDT, was higher than the Acceptable Daily Intake proposed by the WHO.

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Section: Correlations Between Total Ddt In Breast Milk Vs Age and Vssupporting

confidence: 82%

Section: Differences In Total Ddt Concentration Between Primipara Andmentioning

confidence: 57%

DDT and its metabolites in breast milk from the Madeira River basin in the Amazon, Brazil

et al. 2008

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“…Levels of TEQs (mean = 62 pg/g in primapara mothers) and PCBs (mean = 240 ng/g in primapara mothers) in the dumping site milk from Kolkata were notably higher than those from Chennai, indicating that the magnitude of pollution by these contaminants in Indian dumping sites could be different between each other, depending upon the local conditions. Yet another comparison with the Asian developed nation, Japan (Kunisue et al, 2006b) showed that the residents near Kolkata dumping site have been exposed to relatively higher levels of DRCs and PCBs when compared with the general public of Japan.…”

Section: Organohalogens In the Human Breast Milk Samples Collected Frmentioning

confidence: 99%

Recent status of organohalogens, heavy metals and PAHs pollution in specific locations in India

2015

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“…Stuetz et al (2001); 2Nasir et al (1998); 3 Chao et al (2006); 4 Burke et al (2003a); 5 Kalantsi et al (2004); 6 Ennaceur et al (2007); 7 Tsydenova et al (2007); 8Kunisue et al (2006); 9Waliszewski et al (1996);10 Waliszewski et al (1999);11 Waliszewski et al (2002) …”

mentioning

confidence: 99%

Organochlorine Pesticides and Polychlorinated Biphenyls Levels in Human Milk from Chelem, Yucatán, México

Rodas-Ortíz

Ceja-Moreno

González-Navarrete

et al. 2008

Bull Environ Contam Toxicol

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Organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in human milk from Chelem, Yucatan, Mexico were analyzed. Relatively high levels of p,p'-DDE, gamma-chlordane, beta-hexacyclohexane (beta-HCH) and PCB congeners 170, 28, and 44 were found. Concentration profiles by OCP groups followed the next order: SigmaDDTs > SigmaChlordanes > SigmaHCHs > SigmaChlorobenzenes > SigmaDrins. Total OCPs showed a decreasing tendency with number of births (primipara and multipara and age ranks) but these differences were not significant. SigmaDDT levels were lower than in other studies in Mexico, but 36% of the samples exceeded the JMPR-FAO/WHO acceptable daily intake (ADI). About 60.53% of samples exceeded the ADI value for heptachlors.

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Contamination status of persistent organochlorines in human breast milk from Japan: Recent levels and temporal trend

Cited by 92 publications

References 17 publications

DDT and its metabolites in breast milk from the Madeira River basin in the Amazon, Brazil

DDT and its metabolites in breast milk from the Madeira River basin in the Amazon, Brazil

Recent status of organohalogens, heavy metals and PAHs pollution in specific locations in India

Organochlorine Pesticides and Polychlorinated Biphenyls Levels in Human Milk from Chelem, Yucatán, México

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