Contaminants in fishes from Great Lakes-influenced sections and above dams of three Michigan rivers. II: Implications for health of mink

Giesy, John P.; Verbrugge, David A.; Othout, R. A.; Bowerman, William W.; Mora, Miguel A.; Jones, Paul D.; Newsted, John L.; Vandervoort, Christine; Heaton, S. N.; Aulerich, R. J.; Bursian, S. J.; Ludwig, James P.; Dawson, Gary A.; Kubiak, Timothy J.; Best, David Albert; Tillitt, Donald E.

doi:10.1007/bf00214265

Cited by 58 publications

(48 citation statements)

References 58 publications

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“…Similarly, the HI estimated for bald eagles and mink based on contaminant concentrations in fish from three Michigan rivers indicated that PCBs were the critical contaminants of concern (Giesy et al 1994c. In addition to PCBs, mercury in mink and dieldrin in bald eagles are of concern.…”

Section: Hazard Assessmentmentioning

confidence: 98%

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Concentrations and Hazard Assessment of Organochlorine Contaminants and Mercury in Smallmouth Bass from a Remote Lake in the Upper Peninsula of Michigan

Henry

Kannan

Nagy

et al. 1998

Arch Environ Contam Toxicol

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Concentrations of PCBs, DDTs, toxaphene, chlordanes, dieldrin, and mercury were determined in smallmouth bass (Micropterus dolomieui) collected from Fumee Lake, a remote lake in the Upper Peninsula of Michigan. An ecological hazard assessment was conducted to determine potential impacts of contaminants on bald eagles and mink eating fish from this lake. Concentrations of organochlorines, except toxaphene, and mercury in smallmouth bass were similar to those found in fish from Lake Superior, where atmospheric inputs are the primary sources. Bioaccumulation was indicated by a positive correlation between fish weight and contaminant concentrations for organochlorines, while mercury concentrations did not appear to correspond predictably to body weight. Concentrations of mercury and PCBs in smallmouth bass were sufficiently great to be of concern regarding their consumption by eagles or mink.

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Section: Hazard Assessmentmentioning

confidence: 98%

“…Calculated HI are based on the assumption that the diet of predator species is comprised of 100% smallmouth bass. NOAEC values have been reported for mink (Giesy et al 1994c) and bald eagles Bowerman et al 1995) and were based on laboratory feeding studies.…”

Section: Hazard Indicesmentioning

confidence: 99%

Concentrations and Hazard Assessment of Organochlorine Contaminants and Mercury in Smallmouth Bass from a Remote Lake in the Upper Peninsula of Michigan

Henry

Kannan

Nagy

et al. 1998

Arch Environ Contam Toxicol

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“…Exposure to low levels of compounds exhibiting a weak estrogenic activity (ie, polychlorinated biphenyls [PCBs], l,l,l-trichloro-2,2-bis(p-chlorophenyl)ethane [ industrial chemicals and adverse effects operating via the endocrine system has so far not been proved scientifically (2,76 (24,29).…”

Section: Introductionmentioning

confidence: 99%

Endocrine Modulators in the Food Chain and Environment

Nilsson

2000

Toxicol Pathol

108

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“…This is supported by studies in mink comparing the effect of technical PCB mixtures with weathered PCB mixtures, consisting of either meat from rabbits treated with Aroclor 1254 (Aulerich et al, 1986), or meat from fish treated with technical PCB mixtures (Giesy et al, 1994;Giesy and Kannan, 1998). In the study of Aulerich et al (1986), the 28-days LC 50 of Aroclor 1254 was 79 mg/kg feed and the corresponding LC 50 based on meat from rabbits administered Aroclor 1254, was 47 mg/kg feed.…”

Section: Minkmentioning

confidence: 94%

Untitled

2005

EFSA Journal

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SUMMARYPolychlorinated biphenyls (PCB) cover a group of 209 different PCB congeners which can be divided into two groups according to their toxicological properties. One group, consisting of 12 congeners, show toxicological properties similar to dioxins, is therefore termed "dioxinlike PCB" (DL-PCB), and these have been included in the "Risk Assessment of Dioxins and Dioxin-Like PCBs in Food" performed by the EU Scientific Committee on Food (SCF). The other PCB, referred to as "non dioxin-like PCB" (NDL-PCB), have not been previously evaluated by the SCF or EFSA. Both groups of PCB, NDL-PCB as well DL-PCB, are usually found in feed and food.PCB were widely used in a number of industrial and commercial applications. It is estimated that more than 1 million tons of technical PCB mixtures were produced world-wide since their first commercial use in the late 1920s. Although produced by comparable production processes, technical PCB mixtures contain both DL and NDL-PCB and may vary considerably with respect to their congener composition due to differences in the amount of chlorine and the reaction conditions applied. Moreover, technical PCB mixtures contain other dioxin-like compounds as impurities, such as polychlorinated dibenzofurans (PCDF). The different compositions as well as the presence of toxicologically relevant impurities may have a significant impact on the results of toxicological studies with technical PCB mixtures.Although the manufacture, processing and distribution of PCB has been prohibited in almost all industrial countries since the late 1980s, their entry into the environment still occurs, especially due to improper disposal practices or leaks in electrical equipment and hydraulic systems still in use. PCB are highly persistent and are globally circulated by atmospheric transport and thus are present in all environmental media.Data on the occurrence of NDL-PCB in food and feed have been reported in different ways for example as the sum of three PCB congeners (PCB 138, 153 and 180), as the sum of six PCB congeners (PCB 28, 52, 101, 138, 153, 180) often referred to as indicator PCB or as the sum of seven (sum of six indicator PCB plus PCB 118). This lack of consistency often hampers a direct comparison of occurrence data. The Panel decided to use the sum of the six indicator PCB as the basis for the evaluation in this opinion, because these congeners are appropriate indicators for different PCB patterns in various sample matrices and are most suitable for a risk assessment of NDL-PCB on the basis of the available data. The Panel noted that the sum of the six indicator PCB represents about 50% of total NDL-PCB in food.Following exposure of farm animals, NDL-PCB will accumulate in meat, liver and particularly in fat tissues. In addition, NDL-PCB will be transferred into milk and eggs, and levels in these products will reach a steady state following exposure over a period of several weeks. PCB 138 and 153, both with six chlorine atoms, show the highest carry-over into milk and eggs, in the order of 5...

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Contaminants in fishes from Great Lakes-influenced sections and above dams of three Michigan rivers. II: Implications for health of mink

Cited by 58 publications

References 58 publications

Concentrations and Hazard Assessment of Organochlorine Contaminants and Mercury in Smallmouth Bass from a Remote Lake in the Upper Peninsula of Michigan

Concentrations and Hazard Assessment of Organochlorine Contaminants and Mercury in Smallmouth Bass from a Remote Lake in the Upper Peninsula of Michigan

Endocrine Modulators in the Food Chain and Environment

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