Contact Urticaria, Allergic Contact Dermatitis, and Photoallergic Contact Dermatitis from Oxybenzone

Landers, Maeran Chung; Law, Sandra; Storrs, Frances J.

doi:10.2310/6620.2003.38769

Cited by 19 publications

(11 citation statements)

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“…Benzophenone‐3 was the most frequent cause of photocontact allergy in several reports. Other types of hypersensitivity reactions to it have been reported: contact allergy, photocontact urticaria, and contact urticaria (2). Two earlier cases of contact anaphylaxis induced by benzophenone‐3 have been reported (3, 4).…”

Section: Discussionmentioning

confidence: 99%

Anaphylaxis caused by topical application of a sunscreen containing benzophenone‐3

et al. 2008

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Section: Discussionmentioning

confidence: 99%

Anaphylaxis caused by topical application of a sunscreen containing benzophenone‐3

et al. 2008

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“…Some of the problems associated with OXB (and shared by other sunscreens) include increasing reports of cases of photoallergy (44–47). A brief literature survey of epidemiological dermatology reveals that OXB is second only to PABA in the number of reported cases of photoallergy.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, the molar absorption coefficient is relatively low and the absorption spectrum is solvent dependent; in nonpolar environments the spectrum is highly structured resulting in transmission windows in the effective UVR protection range. Some of the problems associated with OXB (and shared by other sunscreens) include increasing reports of cases of photoallergy (44)(45)(46)(47). A brief literature survey of epidemiological dermatology reveals that OXB is second only to PABA in the number of reported cases of photoallergy.…”

Section: Discussionmentioning

confidence: 99%

Reducing Adverse Effects from UV Sunscreens by Zeolite Encapsulation: Comparison of Oxybenzone in Solution and in Zeolites

Chrétien

Heafey

Scaiano

2010

Photochem & Photobiology

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Oxybenzone (OXB) is one of the most widely employed sunscreen ingredients, yet its allowed load is limited to a maximum of 6% reflecting the frequency with which adverse effects are reported. From a spectroscopic point of view, OXB has excellent absorption properties in both the UVB and UVA regions. We propose that zeolite encapsulation can lead to a sunscreen composite ingredient, that we describe as a supramolecular sunscreen, that will retain the excellent spectroscopic properties of OXB, while preventing contact between the skin and the active ingredient. OXB is very photostable, with the only photodegradative pathway observed being the monophotonic photoejection of electrons that leads to trace yields of phenoxyl radicals; this trace reaction is so minor that it cannot be detected from the recovery of unreacted OXB following UV exposure. Solution, as well as powder and in vitro studies of the supramolecular sunscreen, demonstrate that the protective properties of OXB are totally preserved when encapsulated in zeolite NaY.

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“…Skin reactions to sunscreen chemicals include CU, and allergic and photo‐allergic contact dermatitis ; reactions have been found to, for example, benzophenone‐3 (INCI; syn. 2‐hydroxy 4‐methoxy benzophenone, oxybenzone), a common ultraviolet (UV) A/UVB sunscreen, the presence of which also needs to be labeled separately on the cosmetic packaging .…”

Section: Cosmetic Components Causing Cu And/or Cusmentioning

confidence: 99%

Cosmetic components causing contact urticaria: a review and update

Verhulst

Goossens

2016

Contact Dermatitis

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Summary Immediate skin reactions are common in dermatological practice, but may often be overlooked. The main objective of this article is to provide an update of the literature concerning immediate‐type reactions or contact urticaria/contact urticaria syndrome caused by cosmetic ingredients in terms of immediate clinical symptoms, positive reactions following open, scratch or, most often, prick testing, and sometimes the detection of specific IgE antibodies. To this end, a selective search in different medical literature databases was performed. This yielded a list of cosmetic ingredients causing immediate reactions, including hair dyes and bleaches, preservatives, fragrance and aroma chemicals, sunscreens, hair glues, plant‐derived and animal‐derived components, permanent makeup and tattoos, glycolic acid peel, lip plumper, and alcohols. Many of the reported cases, however, lack appropriate controls and detailed investigation. Contact urticaria may occur with or without systemic symptoms, which are sometimes life‐threatening.

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Contact Urticaria, Allergic Contact Dermatitis, and Photoallergic Contact Dermatitis from Oxybenzone

Cited by 19 publications

References 0 publications

Anaphylaxis caused by topical application of a sunscreen containing benzophenone‐3

Anaphylaxis caused by topical application of a sunscreen containing benzophenone‐3

Reducing Adverse Effects from UV Sunscreens by Zeolite Encapsulation: Comparison of Oxybenzone in Solution and in Zeolites

Cosmetic components causing contact urticaria: a review and update

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