Contact Ulcer of the Larynx

Brodnitz, Friedrich S.

doi:10.1001/archotol.1961.00740030073013

Cited by 26 publications

(12 citation statements)

References 18 publications

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“…Moreover, according to some previous studies, allergic adults rarely complain of hoarseness and evidence for laryngeal allergic reaction triggered by airborne allergens seems rare (17). Thus voice disorders in allergic adults were interpreted to be secondary to impairment of nasal breathing and resonance (17). Other authors of more recent studies (18,19) interpreted dysphonia in allergic patients as sign of laryngeal reaction since they reported vocal fold edema as being a common feature in an allergic population.…”

Section: Possible Mechanisms Of Dysphonia In Our Patientsmentioning

confidence: 99%

“…Indeed, the human vocal folds seem to be less prone to allergic reactions since the mast cells involved in allergic response are present mostly in the epiglottis and subglottic regions in the adult larynx (16). Moreover, according to some previous studies, allergic adults rarely complain of hoarseness and evidence for laryngeal allergic reaction triggered by airborne allergens seems rare (17). Thus voice disorders in allergic adults were interpreted to be secondary to impairment of nasal breathing and resonance (17).…”

Section: Possible Mechanisms Of Dysphonia In Our Patientsmentioning

confidence: 99%

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Hoarseness as a Sign of Possible Nonspecific Mucosal Hyperreactivity in Vocal Tract

2009

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The aim of the present paper was to evaluate the possible impact of methacholine challenge on the voice and vocal tract in ten patients reporting hoarseness due to presumable hyperreactivity to some environmental factors. Ten age-and gender-matched healthy subjects served as controls. Methacholine was used for hypersensitivity challenge and saline solution (0.9% NaCl) as control substance. Subjects were examined on two separate challenge occasions testing either methacholine in increasing doses (3, 6, 12 mg) or NaCl. Voice recordings, videolaryngoscopy, and measurement of nasal secretion were performed before and after each sniffing session. Subjective complaints were documented. Data were statistically analyzed with three-way analysis of variance (ANOVA) and group comparisons performed. Perceptual analysis of voice recordings showed an increase of the grade of voice disorder in patients after exposure to both substances. Moreover, one of the patients became aphonic and another severely dysphonic after NaCl. No voice quality changes were detected in controls. The videolaryngoscopy findings divergent from normal did not increase in any group. Nasal secretion was significantly higher after sniffing of methacholine than NaCl in both groups. The frequency of subjective complaints was equal in both groups after both substances. However, there was a qualitative difference in the character of the symptoms: the patients complained of throat, vocal and nasal symptoms while the controls complained exclusively of nasal symptoms.The study supports the view that vocal dysfunction after exposure to non-specific environmental irritating factors may be triggered mainly by emotional mechanisms such as off-warding reaction or dissociative disorder. BACKGROUND AND AIM

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Section: Possible Mechanisms Of Dysphonia In Our Patientsmentioning

confidence: 99%

Section: Possible Mechanisms Of Dysphonia In Our Patientsmentioning

confidence: 99%

Hoarseness as a Sign of Possible Nonspecific Mucosal Hyperreactivity in Vocal Tract

2009

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“…Das Kontaktgranulom tritt bevorzugt bei Männern im mittleren Alter auf [5,13,16]. Hinsichtlich Alter, Geschlecht wie auch Häufung der linksseitigen Lokalisation der Granulation stimmt das vorliegende klinische Gesamtkollektiv (n=45) mit der Literatur überein [23].…”

Section: Diskussionunclassified

“…Retrospektiv wurde dies als "poor therapeutic approach" erkannt [1,5]. Bestenfalls könne hierdurch eine temporäre Heilung der organischen Läsion erzielt werden, im ungünstigsten Fall jedoch die Therapie in einer Atrophie der laryngealen Muskulatur enden.Eine weitere emotionale Belastung sei die Folge; der Patient werden im übrigen mit seinem Mißbrauch der Stimme bzw.…”

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Ein Follow-up von Patienten mit laryngealem Kontaktgranulom

Kiese-Himmel

Kruse

1997

HNO

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A conservative approach (vocal rest, voice therapy, antibiotic treatment of infections and/or management of esophageal reflux) and microsurgery have been used to heal laryngeal contact granulomas. Unfortunately, recurrences have been found in most cases. In the present study we followed 45 patients after an initial diagnosis of a contact granuloma was made based on laryngoscopy and stroboscopy with video-documentation. All studies were conducted in the Department of Phoniatrics (University of Göttingen) during the past four years, with follow-ups made at 3 month-intervals up to 12 months after diagnosis. All patients were counselled using a focal psychosomatic approach. Follow-up was possible for 41 patients. Findings showed that 19 patients lost their contact granulomas completely without therapy, 12 of which occurred over a period to 13 months after diagnosis. Seven patients underwent microsurgery at their own requests, with 5 developing recurrences when compared with the first diagnosis, 15 patients still had a contact granuloma. Emotional strain in connection with specific personality traits seemed to operate as a significant variable in the remission of contact granulomas.

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“…König and von Leden [1961] have confirmed the presence of autonomic end fibers in the mucosa and the musculus vocalis, particularly in the posterior third of the vocal cords. The tonus of the laryngeal striated muscles changes under the influence of the autonomic nervous system [Brodnitz, 1971], Dysphonia induced by external irritants may also be due to reflective change in the laryngeal functions. The activity of the la ryngeal motoneurons located in the nucleus ambiguous is influenced by reflexogenic in puts from various receptor systems located within the larynx itself and within the lungs [Wyke and Kirschner, 1976].…”

Section: Introductionmentioning

confidence: 99%

Provoked Laryngeal Dysfunction

Haapanen¹

1990

Folia Phoniatr Logop

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Contact Ulcer of the Larynx

Cited by 26 publications

References 18 publications

Hoarseness as a Sign of Possible Nonspecific Mucosal Hyperreactivity in Vocal Tract

Hoarseness as a Sign of Possible Nonspecific Mucosal Hyperreactivity in Vocal Tract

Ein Follow-up von Patienten mit laryngealem Kontaktgranulom

Provoked Laryngeal Dysfunction

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