Contact Sensitivity to Sorbic acid in 'Unguentum Merck'

Occupational contact dermatitis from potassium sorbate in milk transformation plant

“…1) such as potassium, calcium and sodium inhibit moulds and yeasts, and are used as preservatives to avoid further fermentation in tobacco and foods such as wines, butter, cheese, yoghurts or dried fruits … (1, 2). In cosmetics (3) and pharmaceuticals (4), they are used mainly in fatty acids and polyoxyethylene‐based products (5). Those chemicals also improve milling characteristics in cold rubber, and may be used in copolymerization, as intermediate for plasticizers and lubricants, in adhesives, glues, inks, paints, varnishes, tanning agents and metalworking fluids (1).…”

Compound allergy to Unguentum M®

“…Allergic contact dermatitis from Unguentum M ® is unusual. 3 cases have previously been reported from the preservative, sorbic acid (1–3), and 1 case from the suspension agent, silicic acid (4). To our knowledge, compound allergy to Unguentum M ® has not previously been reported.…”

Another case of sorbic acid sensitivity

“…1971). A further case was reported by Saihan & Harman (1978). Messrs. Merck know of only three cases of confirmed sorbic acid sensitivity associated with a 4-year use of Unguentum Merck.…”