Contact sensitivity in patients with venous leg ulcers in Serbia: comparison with contact dermatitis patients and relationship to ulcer duration

Jankicevic, Jasmina; Vesić, Sonja; Vukičević, Jelica; Gajić, Miodrag; Adamič, Metka; Pavlović, Miloš

doi:10.1111/j.1600-0536.2007.01253.x

Cited by 38 publications

(32 citation statements)

References 21 publications

(55 reference statements)

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“…The cause of the persistent high incidence of hypersensitivity to Balsam of Peru is mainly due to regional practices in topical therapy, where it is contained in some external medicinal products for its antiseptic effect and is very popular in non-dermatological clinics for treating various types of chronic wounds. ACD around leg ulcers is most commonly caused by this allergen [14][15][16] . The third most common allergen was a mixture of fragrant substances, fragrance-mix I (7.1%).…”

Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Tichý¹,

Karlová²

2015

BIOMED PAP

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and evaluate their dynamics in comparison with similar studies in the Czech Republic and internationally carried out in previous years. Methods. A total of 1941 patients with suspected ACD were examined using the patch tests from the European Standard Series. The data obtained were subjected to statistical analysis. Results. The most common contact allergy was to nickel (15.4%), the second most frequent allergen was Balsam of Peru (11.6%). The top five allergens in the whole sample also included, in descending order, fragrance-mix I (7.1%), cobalt chloride (6.4%), and Kathon CG (4.0%). While the order of contact allergens causing sensitisation in women is consistent with the results of the whole sample, in men instead of cobalt and Kathon CG, epoxy resin and chromium appeared among the five most common allergens. Conclusions. In the Czech Republic, despite existing EU legislation, action to reduce the frequency of sensitization to nickel failed in contrast to other EU countries. In addition to nickel, consistent preventive measures should be focused mainly on sensitization to Balsam of Peru, cobalt, epoxy resins, chromium and aromatic substances and preservatives used in the cosmetic industry.

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Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Tichý¹,

Karlová²

2015

BIOMED PAP

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“…The allergen could not be identified as it is not declared but we hypothesize that it might be the release of ionic silver contained in both dressings. Sensitization to silver has been described 7,8 but is very rare. We observed 11 doubtful (“equivocal”) reactions within the ‘hypoallergenic’ wound dressings as crescendo reaction after 72 h, four of them with the silver containing dressings Contreet ® ( n = 2), Aquacel Ag ® and Prisma ® ( n = 1 each).…”

Section: Hit List Of Positive Results Of the Standard Series Ointmementioning

confidence: 99%

Contact allergy to modern wound dressings: a persistent but neglected problem

Renner

Simon

Seikowksi³

et al. 2011

Acad Dermatol Venereol

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and women exposed during the second and third trimester should probably be split for analysis. 2 According to the FDA, adalimumab (like all anti-TNF-a agents) is a category B drug in pregnancy (animal studies have failed to demonstrate a risk to the fetus but there are no adequate and wellcontrolled studies of the effect of the drug on pregnant women). 3 However, anti-TNF antibodies are species-specific and only few human reports are available. 8

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“…Of allergens tested for contact sensitivity in patients with venous leg ulcers, chloramphenicol was one of the most commonly implicated [56].…”

Section: Immunologicmentioning

confidence: 99%

Chloramphenicol

2016

Meyler's Side Effects of Drugs

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Contact sensitivity in patients with venous leg ulcers in Serbia: comparison with contact dermatitis patients and relationship to ulcer duration

Abstract: The results confirm a high rate of contact (poly)sensitization in patients with CVLU and local variability in allergen prevalence.

Cited by 38 publications

References 21 publications

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Allergic contact dermatitis and changes in the frequency of the causative allergens demonstrated with patch testing in 2008-2012

Contact allergy to modern wound dressings: a persistent but neglected problem

Chloramphenicol

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