2018
DOI: 10.1167/iovs.17-23685
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Contact Lens-Associated Dry Eye Disease: Recent Advances Worldwide and in Japan

Abstract: Contact lens wearers complain of various types of contact lens discomfort (CLD), which may result in the discontinuation of contact lenses. CLD is often associated with dry eye disease. A contact lens divides the tear film into two layers: the pre-and post-lens tear film. This change leads to instability of the pre-lens tear film, thinning of pre-and post-lens tear film thickness, and increased friction between the contact lens and the ocular surface. The Japanese Dry Eye Society recommends the diagnosis of te… Show more

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Cited by 87 publications
(79 citation statements)
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“…35 Any homeostatic imbalance caused by ocular surface conditions, such as dry eye or meibomian gland dysfunction, can become exacerbated by a contact lens and lead to contact lens discomfort or contact lens-induced dry eye. 23,36 This issue as it relates to contact lens dropout has been specifically analyzed by Giannaccare et al (2016) via a retrospective analysis (n = 87). 37 The authors found that compared to controls, subjects who had discontinued contact lens wear had lower/worse tear break up time and Schirmer test values, and higher/worse ocular surface disease index (OSDI) and corneal staining scores.…”
Section: Ocular Surface Factorsmentioning
confidence: 99%
“…35 Any homeostatic imbalance caused by ocular surface conditions, such as dry eye or meibomian gland dysfunction, can become exacerbated by a contact lens and lead to contact lens discomfort or contact lens-induced dry eye. 23,36 This issue as it relates to contact lens dropout has been specifically analyzed by Giannaccare et al (2016) via a retrospective analysis (n = 87). 37 The authors found that compared to controls, subjects who had discontinued contact lens wear had lower/worse tear break up time and Schirmer test values, and higher/worse ocular surface disease index (OSDI) and corneal staining scores.…”
Section: Ocular Surface Factorsmentioning
confidence: 99%
“…Alternative environmental factors, like poor ergonomics, improper lighting, glare, cut wetness in air-conditioned rooms, 28 are all tributary factors for worsening of those symptoms. Uncorrected refractive errors, 29 contact-lens wearers, 30 people with a history of ocular illnesses, 31 diabetics, 32 female gender, 33 and autoimmune diseases are at risk for the development of more and severe symptoms than their age-matched counterparts.…”
Section: Why/how Do Screens Cause Eyestrain?mentioning
confidence: 99%
“…Decreased tear film stability as measured with tear film BUT occurs with long term use of contact lenses stability. In a recent study, ocular discomfort and other dry eye symptoms were present in contact lens wearers 20 . The reason might be the daily wearing time of soft contact lens induced hypoxia and caused disturbances in pre corneal tear film stability.…”
Section: Discussionmentioning
confidence: 93%