2007
DOI: 10.1109/tcsi.2007.902409
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Contact Imaging: Simulation and Experiment

Abstract: We report simulated and experimental image quality for contact imaging, a method for imaging objects close to the sensor surface without intervening optics. This technique preserves microscale resolution for applications that can not tolerate the size or weight of conventional optical elements. In order to assess image quality, we investigated the spatial resolution of contact imaging, which depends on the sensor size as well as the distance between objects and the sensor surface. We studied how this distance … Show more

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Cited by 55 publications
(35 citation statements)
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References 43 publications
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“…As analyzed in [6,7,8,9,10,11], the spatial resolution can be improved by increasing D ls , or decreasing D obj and D PIX . D ls can be as long as several centimeters, which is mainly determined by the size of the POCT system.…”
Section: Introductionmentioning
confidence: 99%
“…As analyzed in [6,7,8,9,10,11], the spatial resolution can be improved by increasing D ls , or decreasing D obj and D PIX . D ls can be as long as several centimeters, which is mainly determined by the size of the POCT system.…”
Section: Introductionmentioning
confidence: 99%
“…The system model work in [4] assumes that the pixel DR performance is good enough to cover the image intensity range, and the pixel size is smaller than FWHM of the intensity profiles. However, the pixel DR needs to cover the maximum image intensity range.…”
Section: B Dynamic Range Modelmentioning
confidence: 99%
“…This leads to one fundamental limitation in the existing lensless microfluidic imaging systems: a large CIS pixel has better dynamic range (DR) or sensitivity, but results in a poor spatial resolution. Therefore, the trade-off between system spatial resolution and DR (or sensitivity) needs to be properly analyzed for optimizing the overall system design [4].…”
Section: Introductionmentioning
confidence: 99%
“…Thus, it is ideal for use in microdevices in which the object(s) of interest and the sensor are of a similar scale. [23][24][25] Efforts in this area have mainly been targeted at providing contact images of particles, cells, and other biological entities. Kovacs and co-workers were the first to demonstrate the use of shadow images from a camera chip attached to the bottom of a microfluidic culture chamber to monitor the activity of Caenorhabditis elegans nematodes (typical length, approximately 1 mm) that were maintained in a microfluidic environment.…”
mentioning
confidence: 99%