Contact erythema multiforme from Primula obconica

Erythema multiforme‐like contact dermatitis from primin

“…The typical pattern consists of linear streaks of erythema, vesicles, and bullae. Various authors have reported an eruption resembling erythema multiforme (3, 4, 15), like the one presented here. The differential clinicohistopathological features of true erythema multiforme and erythema multiforme‐like contact reactions are shown in Table 1(16, 17).…”

“…Contact allergy to primin has always been rare in Italy; the substance has never been included in the baseline patch test series (3, 4). In our clinic, we have seen five cases, all occupational, since 1980, of about 200 patients tested with primin on the basis of their clinical history.…”

An unusual clinical presentation of allergic contact dermatitis to common ivy

“…This peculiar clinical presentation is most often described with strong allergens and the initial dermatitis may resemble an usual eczematous morphologic pattern followed by distant lesions on skin without contact showing erythema multiforme‐like appearance . Such an atypical clinical pattern has been previously reported with some plants, including primrose, exotic woods, poison ivy, and more recently, Geranium robertianum , but not with common ivy, to the best of our knowledge . As suggested by some authors, it would be relevant to include falcarinol in the plant series testing owing to the relatively high frequency of common ivy‐related allergic contact dermatitis in Europe …”

Noneczematous Contact Dermatitis

“…Inula helenium , contained in a mixture to treat back pain, has also induced erythema multiforme-like eruption, with positive patch tests to sesquiterpene lactone mix and alantolactone [19]. Notably, Primula obconica can also induce comparable eruptions [20–23]. We observed an erythema multiforme-like reaction in a plant nursery worker, who had handled plants of P. obconica .…”