Contact dermatitis from pilocarpine

Cusano, Francesco; Luciano, S.; Capozzi, Maria Annunziata M.; Verrilli, D. A.

doi:10.1111/j.1600-0536.1993.tb03495.x

Cited by 24 publications

(14 citation statements)

References 2 publications

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“…Basic, active, and additive agents of ophthalmic preparations are known allergens of the periorbital region. Most frequent ophthalmic allergens are phenylephrine, betablockers, antibiotics, resorcine, pilocarpine, thiomersal, chloramphenicol, and antazoline 35–39 . PD as occupational skin disease can be mainly observed in dental, cosmetic, wood and food industry, and in animal husbandry 40–42 .…”

Section: Introductionmentioning

confidence: 99%

“…Most frequent ophthalmic allergens are phenylephrine, betablockers, antibiotics, resorcine, pilocarpine, thiomersal, chloramphenicol, and antazoline. [35][36][37][38][39] PD as occupational skin disease can be mainly observed in dental, cosmetic, wood and food industry, and in animal husbandry. [40][41][42] Plants and herbs may also cause PD: in case of allergy, exposure to the powder, extractum, and/or the pollen of the particular plant provokes contact dermatitis of the region.…”

Section: Introductionmentioning

confidence: 99%

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Periocular dermatitis: a report of 401 patients

Temesvári

Pónyai

Németh

et al. 2009

Acad Dermatol Venereol

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The occurence of contact hypersensitivity in PD patients was in present study 34.4%. A relatively high occurrence was seen in cases of PD without other symptoms, in PD + OC and in PD + AD patients. The predominance of environmental contact allergens was remarkable: most frequent sensitizers were nickel sulphate, fragrance mix I, balsam of Peru, thiomersal, and PPD. The prevalence of contact hypersensitivity to ophthalmic allergens did not exceed l.5%.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Periocular dermatitis: a report of 401 patients

Temesvári

Pónyai

Németh

et al. 2009

Acad Dermatol Venereol

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“…There are reports of delayed allergic contact dermatitis in patients using ophthalmic pilocarpine solutions. [2][3][4] To our knowledge, pilocarpine has not been previously reported to cause urticaria in the setting of sweat testing. We describe a case of urticaria that was successfully prevented upon retesting using an H 1 antihistamine.…”

Section: Introductionmentioning

confidence: 89%

Urticaria associated with the pilocarpine iontophoresis sweat test

LeGrys

Retsch‐Bogart

1997

Pediatr. Pulmonol.

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“…In the case reported by Muñoz-Bellido et al [12], clinical features and positive results at 15-and 30-minute readings of patch testing with cyclopentolate hydrochloride allowed the diagnosis of contact urticaria. Only 3 cases of allergic contact dermatitis to pilocarpine confirmed by patch tests have been reported [13][14][15]. In particular, one subject reacted positively after repeated open application tests [15].…”

Section: Parasympathomimeticsmentioning

confidence: 96%

“…Only 3 cases of allergic contact dermatitis to pilocarpine confirmed by patch tests have been reported [13][14][15]. In particular, one subject reacted positively after repeated open application tests [15].…”

Section: Parasympathomimeticsmentioning

confidence: 96%

Hypersensitivity Reactions to Ophthalmic Products

Ventura

Viola

Gaeta

et al. 2006

CPD

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Adverse reactions after administration of ophthalmic products have frequently been observed. These reactions can be provoked by both active principles and excipients. Different pathogenic mechanisms have been suggested for such reactions, including immunologic ones. Basophils and mast cells participate in IgE-mediated reactions through the release of mediators like histamine and tryptase, whereas a T-cell-mediated pathogenic mechanism is involved in most delayed reactions, particularly conjunctival ones and eyelid dermatitis. Prick tests and immediate-reading intradermal tests are carried out to diagnose immediate hypersensitivity reactions, while patch tests are usually performed to evaluate delayed reactions. Other diagnostic tests, such as serum-specific IgE assays in immediate reactions, as well as delayed-reading intradermal tests and/or lymphocyte transformation tests in delayed ones, are rarely performed. In this review, particular attention is addressed to the clinical and practical aspects of both cell-mediated and IgE-mediated hypersensitivity reactions to ophthalmic products.

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Contact dermatitis from pilocarpine

Cited by 24 publications

References 2 publications

Periocular dermatitis: a report of 401 patients

Periocular dermatitis: a report of 401 patients

Urticaria associated with the pilocarpine iontophoresis sweat test

Hypersensitivity Reactions to Ophthalmic Products

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