Consumption of non-nutritive sweeteners during pregnancy

Palatnik, Anna; Moosreiner, Andrea; Stichelen, Stéphanie Olivier-Van

doi:10.1016/j.ajog.2020.03.034

Cited by 30 publications

(16 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…sucralose, thaumatin, monk fruit). 25 The effects of artificial sweeteners on the gut microbiome are diverse, including impacts on composition and function (see Suez et al 26 for a synthesis). Suez et al 27 also demonstrated that artificial sweetener consumption in adult mice directly impacts gut microbiome composition and function, leading to an increase in host glucose intolerance.…”

Section: Introductionmentioning

confidence: 99%

Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index

et al. 2020

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Observational human studies regarding AS and NNS exposure are often difficult to interpret because of heterogeneity and the lack of accuracy of self-reported intake of AS and NNS. In NGTP, some issues of concern, including increased infant BMI, childhood obesity, and small increase in preterm birth, have been observed [ 36 ]. Concerning preterm birth, the European Food Safety Authority has concluded that there is no evidence available to support a causal relationship between the consumption of ASBs and preterm delivery [ 37 ].…”

Section: Carbohydratesmentioning

confidence: 99%

Diet and Healthy Lifestyle in the Management of Gestational Diabetes Mellitus

et al. 2020

View full text Add to dashboard Cite

Gestational diabetes mellitus (GDM) among pregnant women increases the risk of both short-term and long-term complications, such as birth complications, babies large for gestational age (LGA), and type 2 diabetes in both mother and offspring. Lifestyle changes are essential in the management of GDM. In this review, we seek to provide an overview of the lifestyle changes which can be recommended in the management of GDM. The diet recommended for women with GDM should contain sufficient macronutrients and micronutrients to support the growth of the foetus and, at the same time, limit postprandial glucose excursions and encourage appropriate maternal gestational weight gain. Blood glucose excursions and hyperglycaemic episodes depend on carbohydrate-intake. Therefore, nutritional counselling should focus on the type, amount, and distribution of carbohydrates in the diet. Further, physical activity has beneficial effects on glucose and insulin levels and it can contribute to a better glycaemic control.

show abstract

“…For example, it has been shown that maternal diet and nutrition patterns early in life predispose to increased cardiovascular risk, metabolic disorders, and immune impairment [42][43][44]. Moreover, insufficient intake of fruits and vegetables and high consumption of modern processed foods during pregnancy have been associated with systemic low-grade systematic inflammation [45,46]. Such maternal inflammation is believed to pass an inflammatory 'code' through epigenetic modifications to the offspring and influence the programming of the offspring's immune system [47].…”

Section: Non-imprinting Epigenetic Changes In Prenatal Lifementioning

confidence: 99%

Epigenetic Changes Induced by Maternal Factors during Fetal Life: Implication for Type 1 Diabetes

Barchetta

Arvastsson

Sarmiento

et al. 2021

Genes

View full text Add to dashboard Cite

Organ-specific autoimmune diseases, such as type 1 diabetes, are believed to result from T-cell-mediated damage of the target tissue. The immune-mediated tissue injury, in turn, is known to depend on complex interactions between genetic and environmental factors. Nevertheless, the mechanisms whereby environmental factors contribute to the pathogenesis of autoimmune diseases remain elusive and represent a major untapped target to develop novel strategies for disease prevention. Given the impact of the early environment on the developing immune system, epigenetic changes induced by maternal factors during fetal life have been linked to a likelihood of developing an autoimmune disease later in life. In humans, DNA methylation is the epigenetic mechanism most extensively investigated. This review provides an overview of the critical role of DNA methylation changes induced by prenatal maternal conditions contributing to the increased risk of immune-mediated diseases on the offspring, with a particular focus on T1D. A deeper understanding of epigenetic alterations induced by environmental stressors during fetal life may be pivotal for developing targeted prevention strategies of type 1 diabetes by modifying the maternal environment.

show abstract

Consumption of non-nutritive sweeteners during pregnancy

Cited by 30 publications

References 87 publications

Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index

Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index

Diet and Healthy Lifestyle in the Management of Gestational Diabetes Mellitus

Epigenetic Changes Induced by Maternal Factors during Fetal Life: Implication for Type 1 Diabetes

Contact Info

Product

Resources

About