Consumption of fruit and vegetable and risk of coronary heart disease: A meta-analysis of prospective cohort studies

Gan, Yong; Tong, Xiaofeng; Li, Liqing; Cao, Shiyi; Yin, Xiaoxv; Gao, Chao; Herath, Chulani; Li, Wenzhen; Jin, Zhe; Chen, Yawen; Lu, Zuxun

doi:10.1016/j.ijcard.2015.01.077

Cited by 149 publications

(87 citation statements)

References 59 publications

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“…In this study all groups were encouraged to reduce discretionary foods and it appears this advice was followed. A significant finding, however, was that the addition of walnuts in the IW group appeared to aid in increased consumption of vegetables, low fat milk and yoghurt, and less protein rich foods than the I and C groups, which may in itself have advantages [82][83][84][85].…”

Section: Changes In Food Choicesmentioning

confidence: 93%

Changes in diet quality during a 12 month weight loss randomised controlled trial

et al. 2017

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Section: Changes In Food Choicesmentioning

confidence: 93%

Changes in diet quality during a 12 month weight loss randomised controlled trial

et al. 2017

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“…Low fruit and vegetable consumption is an important risk factor for DRDs (90). It is believed that dietary interventions that promote increased consumption of fruits and vegetables could lead to an important decrease in mortality from CVD (89,91).…”

Section: Epidemiologic Studies: Fruit Yogurt and Cardiometabolic Hementioning

confidence: 99%

“…A subsequent meta-analysis examining the association between fruit and vegetable consumption and CAD identified 15 studies with 25 dose-response reports that compared low and high intake of fruit and CAD risk. Of these studies, 6 reported strong inverse relations; pooled analysis revealed a 16% reduction in CAD risk associated with an intake of 300 g fruit/d (91). Several attributes of fruit are credited with heart-protective properties, including nutrient and phytochemical content (e.g., fiber, potassium, and folate), low dietary glycemic load, and energy density (89).…”

Section: Epidemiologic Studies: Fruit Yogurt and Cardiometabolic Hementioning

confidence: 99%

Potential Health Benefits of Combining Yogurt and Fruits Based on Their Probiotic and Prebiotic Properties

Fernandez

Marette

2017

Advances in Nutrition

117

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Fruit and yogurt have been identified individually as indicators of healthy dietary patterns. Fruits are relatively low in energy density and are an excellent source of antioxidants and prebiotic fibers and polyphenols, which can promote digestive health. Yogurt, on the other hand, is a nutrient-dense food that is a good source of dairy protein, calcium, magnesium, vitamin B-12, conjugated linoleic acid, and other key fatty acids. In addition, it contains beneficial bacterial cultures, making it a potential source of probiotics. Yogurt's unique fermented food matrix provides added health benefits by enhancing nutrient absorption and digestion. Combining the intake of yogurt and fruit could provide probiotics, prebiotics, high-quality protein, important fatty acids, and a mixture of vitamins and minerals that have the potential to exert synergistic effects on health. Yogurt consumption has been associated with reduced weight gain and a lower incidence of type 2 diabetes, whereas fruits have established effects on reducing the risk of cardiovascular disease. Yogurt and fruits can be eaten together and may exert combined health benefits through potential prebiotic and probiotic effects. Furthermore, substituting high-energy, nutrient-deficient snacks with fruit and yogurt could reduce the intake of high-calorie obesogenic foods. In light of the positive cardiometabolic impacts of fruit and yogurt and their association with healthy dietary patterns, there is sufficient evidence to warrant further exploration into the potential synergistic health benefits of a combined intake of fruit and yogurt. Adv Nutr 2017;8(Suppl):155S-64S.

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“…Meanwhile, another large cohort study indicated that fruits and vegetables intake can reverse coronary heart disease [21]. Many epidemiological studies indicated that higher serum carotenoid levels have beneficial effects on CVD biomarkers.…”

Section: Epidemiological Studies Of Carotenoidsmentioning

confidence: 99%

Carotenoids Regulate Endothelial Functions and Reduce the Risk of Cardiovascular Disease

Yamagata¹

2017

Carotenoids

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Regular consumption of fruits and vegetables can help reduce the risk for cardiovascular disease (CVD) and its associated mortality. A diet rich in fruits and vegetables is thought to have cardioprotective effects, but the specific components of these foods that provide this protection are unclear. Antioxidants such as vitamin C, carotenoids, and polyphenols in fruits and vegetables likely contribute to the reduction in risk of CVD by minimizing cholesterol oxidation in blood vessel walls. Meanwhile, cardioprotective effects afforded by the carotenoids lycopene, α-carotene, β-carotene, β-cryptoxanthin, lutein, and zeaxanthin have been reported in many studies. Carotenoids are naturally occurring fat-soluble pigments that are present at high levels in tomatoes and carrots. Carotenoids play an important role in staving off atherosclerosis via antioxidant activities that reduce lipid peroxidation in low-density lipoproteins. Lycopene reduces endothelin-1 gene expression by suppressing generation of reactive oxygen species and inducing heme oxygenase-1 expression in human endothelial cells. Thus, carotenoids may mitigate endothelial dysfunction by promoting direct antioxidative effects and inducing expression of several genes. Structural and functional differences among carotenoids may explain their unique biologic activities. In this review, the roles of carotenoids in relation to their influence on vascular endothelial functions and cardioprotective effects are discussed.

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Consumption of fruit and vegetable and risk of coronary heart disease: A meta-analysis of prospective cohort studies

Cited by 149 publications

References 59 publications

Changes in diet quality during a 12 month weight loss randomised controlled trial

Changes in diet quality during a 12 month weight loss randomised controlled trial

Potential Health Benefits of Combining Yogurt and Fruits Based on Their Probiotic and Prebiotic Properties

Carotenoids Regulate Endothelial Functions and Reduce the Risk of Cardiovascular Disease

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