Consumption of Dairy and Metabolic Syndrome Risk in a Convenient Sample of Mexican College Applicants

Mosley, M.; Andrade, Flávia Cristina Drumond; Aradillas‐García, Celia; Terán-García, Margarita

doi:10.4236/fns.2013.41009

Cited by 7 publications

(8 citation statements)

References 45 publications

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“…In our study, a dairy intake of less than 2 servings a week was a risk factor for MetS. This result concurred with findings from Mexican, European, and Middle Eastern populations in which individuals with a higher dairy consumptions had a lower prevalence of MetS [ 38 , 39 ][ 40 ][ 41 ]…”

Section: Discussionsupporting

confidence: 90%

Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome

Zhao

et al. 2016

PLoS ONE

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ObjectiveThe present study investigated the prevalence and risk factors for Metabolic syndrome. We evaluated the association between single nucleotide polymorphisms (SNPs) in the apolipoprotein APOA1/C3/A4/A5 gene cluster and the MetS risk and analyzed the interactions of environmental factors and APOA1/C3/A4/A5 gene cluster polymorphisms with MetS.MethodsA study on the prevalence and risk factors for MetS was conducted using data from a large cross-sectional survey representative of the population of Jilin Province situated in northeastern China. A total of 16,831 participations were randomly chosen by multistage stratified cluster sampling of residents aged from 18 to 79 years in all nine administrative areas of the province. Environmental factors associated with MetS were examined using univariate and multivariate logistic regression analyses based on the weighted sample data. A sub-sample of 1813 survey subjects who met the criteria for MetS patients and 2037 controls from this case-control study were used to evaluate the association between SNPs and MetS risk. Genomic DNA was extracted from peripheral blood lymphocytes, and SNP genotyping was determined by MALDI-TOF-MS. The associations between SNPs and MetS were examined using a case-control study design. The interactions of environmental factors and APOA1/C3/A4/A5 gene cluster polymorphisms with MetS were assessed using multivariate logistic regression analysis.ResultsThe overall adjusted prevalence of MetS was 32.86% in Jilin province. The prevalence of MetS in men was 36.64%, which was significantly higher than the prevalence in women (29.66%). MetS was more common in urban areas (33.86%) than in rural areas (31.80%). The prevalence of MetS significantly increased with age (OR = 8.621, 95%CI = 6.594–11.272). Mental labor (OR = 1.098, 95%CI = 1.008–1.195), current smoking (OR = 1.259, 95%CI = 1.108–1.429), excess salt intake (OR = 1.252, 95%CI = 1.149–1.363), and a fruit and dairy intake less than 2 servings a week were positively associated with MetS (P<0.05). A family history of diabetes (OR = 1.630, 95%CI = 1.484–1.791), cardiovascular disease or cerebral diseases (OR = 1.297, 95%CI = 1.211–1.389) was associated with MetS. APOA1 rs670, APOA5 rs662799 and rs651821 revealed significant differences in genotype distributions between the MetS patients and control subjects. The minor alleles of APOA1 rs670, APOA5 rs662799 and rs651821, and APOA5 rs2075291 were associated with MetS (P<0.0016). APOA1 rs5072 and APOC3 rs5128, APOA5 rs651821 and rs662799 were in strong linkage disequilibrium to each other with r2 greater than 0.8. Five haplotypes were associated with an increased risk of MetS (OR = 1.23, 1.58, 1.80, 1.90, and 1.98). When we investigated the interactions of environmental factors and APOA1/C3/A4/A5 gene cluster gene polymorphisms, we found that APOA5 rs662799 had interactions with tobacco use and alcohol consumption (PGE<0.05).ConclusionsThere was a high prevalence of MetS in the northeast of China. Male gender, increasing age, mental labor, famil...

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Section: Discussionsupporting

confidence: 90%

Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome

Zhao

et al. 2016

PLoS ONE

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“…Twenty two reports were excluded after carefully reading the full texts ( Supplementary Table S1 ). Finally, a total of 23 publications, including 15 cross-sectional studies 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 , one case-control study 27 and seven prospective cohort studies 28 29 30 31 32 33 34 were included in this meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

Dairy products consumption and metabolic syndrome in adults: systematic review and meta-analysis of observational studies

Chen

Szeto

Chen

et al. 2015

Sci Rep

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The association of dairy products consumption with risk of metabolic syndrome (MetS) has been inconsistently reported in observational studies. A systematic review and meta-analysis of published observational studies was conducted to quantitatively evaluate this association. Relevant studies were identified by searching PubMed and EMBASE databases and by carefully checking the bibliographies of retrieved full reports and related reviews. Eligible studies were observational studies that investigated the association between dairy products consumption and risk of MetS in adults, with risk estimates available. Random-effects model was assigned to calculate the summary risk estimates. The final analysis included 15 cross-sectional studies, one case-control study and seven prospective cohort studies. Higher dairy consumption significantly reduced MetS by 17% in the cross-sectional/case-control studies (odds ratio = 0.83, 95% confidence interval [CI], 0.73–0.94), and by 14% (relative risk [RR] = 0.86, 95% CI, 0.79–0.92) in cohort studies. The inverse dairy-MetS association was consistent in subgroup and sensitivity analyses. The dose-response analysis of the cohort studies conferred a significant 6% (RR = 0.94, 95% CI, 0.90–0.98) reduction in the risk of MetS for each increment in dairy consumption of one serving/d. No significant publication bias was observed. Our findings suggest an inverse dose-response relationship between dairy consumption and risk of MetS.

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“…A total of 35 studies including 12 cohort studies [ 22 , 23 , 24 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 ] with 40,943 subjects and 9436 cases and 25 cross-sectional [ 17 , 18 , 19 , 20 , 21 , 25 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 ] studies with 362,196 subjects were included in meta-analyses of the highest versus the lowest dairy product consumption and risk of MetS ( Figure 1 ). Table 3 presents the characteristics of studies included in the meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

“…The natural logarithm of the RRs from the original study were combined through using the DerSimonian and Laird random-effects models, which incorporate both within- and between-study variations [ 16 ]. If the original study did not report the lowest level as a reference, we recalculated the RR and its 95% CI [ 17 , 18 , 19 , 20 , 21 ]. When a study reports the results of normal weight at base line and overweight or obese at baseline, we first combined the two results using a fixed-effect model to obtain an overall estimate before combining with other studies [ 22 , 23 ].…”

Section: Methodsmentioning

confidence: 99%

“…For yogurt consumption, high yogurt consumption was inversely associated with hyperglycemia in adult women (OR: 0.76; 95% CI: 0.61-0.94; p for trend = 0.006) and elderly men (OR: 0.65; 95% CI: 0.43-0.98; p for trend = 0.049). [17][18][19][20][21]25, studies with 362,196 subjects were included in meta-analyses of the highest versus the lowest dairy product consumption and risk of MetS (Figure 1). Table 3 presents the characteristics of studies included in the meta-analysis.…”

Section: Knhanes Analysismentioning

confidence: 99%

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Dairy Consumption and Risk of Metabolic Syndrome: Results from Korean Population and Meta-Analysis

Jin

2021

Nutrients

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Dairy consumption has been associated with decreased risk of metabolic syndrome (MetS) in previous studies, but the association may be different according to each type of dairy products and its subgroups. Thus, we conducted an updated meta-analysis of observational studies to examine the association between various dairy products and risk of MetS. The PubMed and Web of Science databases were searched for eligible studies published up to February 2021. In addition, we included unpublished results from Korea National Health and Nutrition Examination Survey, 2013–2018, including 23,319 Korean adults and the elderly. A total of 35 studies (12 cohort studies and 25 cross-sectional studies) with 398,877 subjects were included in the meta-analysis. The pooled relative risks (RR) of MetS for the highest versus lowest categories of dairy consumption was 0.80 [95% confidence interval (CI): 0.72–0.88]. For the type of dairy products, there were also significant inverse associations with milk (RR: 0.83; 95% CI: 0.78–0.89) and yogurt consumption (RR: 0.89; 95% CI: 0.83–0.95). For cheese consumption, however, no significant association was found (RR: 0.98; 95% CI: 0.86–1.11). Our findings suggest that milk and yogurt consumption is inversely associated with the risk of MetS, but not cheese consumption.

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Consumption of Dairy and Metabolic Syndrome Risk in a Convenient Sample of Mexican College Applicants

Cited by 7 publications

References 45 publications

Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome

Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome

Dairy products consumption and metabolic syndrome in adults: systematic review and meta-analysis of observational studies

Dairy Consumption and Risk of Metabolic Syndrome: Results from Korean Population and Meta-Analysis

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