Consumo de refrigerante reduz a ingestão de alimentos em ratos Wistar

Abstract

Aims:To evaluate the effect of caloric and non-caloric soft drink intake on food consumption, body weight and composition, and metabolic parameters in rats. Methods: Controlled experimental study in which 30 male Wistar rats were divided into three groups and given food and beverage ad libitum during 17 weeks. The groups were as follows, according to the offered food: Control group -standard chow and water; Caloric soft drink group -standard chow, caloric soft drink, and water; and Non-caloric soft drink group -standard chow, non-caloric soft drink, and water. Results: There was no statistical difference in total energy intake, body weight, and fat deposition between groups. However, the chow energy intake was 45% lower in the caloric soft drink group compared to the control and non-caloric soft drink groups (198.7±0.7 kJ vs. 349.4±2.0 and 373.0±1.3 kJ, respectively), with 46% of the energy provided by the soft drink. The caloric soft drink group consumed 22% more carbohydrate, especially sucrose, compared to the control group (p<0.05). Macronutrient intake was not different between the control and non-caloric soft drink groups, but the caloric soft drink group consumed less protein and lipids when compared to the other groups (3.5±1.0 g of protein vs. 6.2±0.1 and 6.7±0.1 g, respectively; 0.7±0.01 g of lipids vs. 1.3±0.02 g and 1.4±0.02 g, respectively). Consumption of non-caloric soft drinks increased total sodium intake and consumption of both soft drinks decreased water intake. Although body weight varied during the experiment, there was no significant difference between groups at the end of the experiment, and no difference in fat deposition, fasting glucose, insulin and leptin, insulin resistance index, and lipid profile. Conclusions: The consumption of both types of soft drinks did not affect energy intake, body weight and composition, or metabolic parameters; however, it increased fluid intake and decreased water ingestion. Caloric soft drink intake influenced the amount and the quality of solid food consumed, compromising diet quality.KEY WORDS: soft drinks; food consumption; macronutrients. RESUMOObjetivos: Avaliar o efeito do consumo de refrigerante calórico e não calórico sobre a ingestão alimentar, composição corporal, massa corporal e parâmetros metabólicos em ratos. Métodos: Estudo experimental com grupo controle. Trinta ratos Wistar machos foram divididos em três grupos e receberam alimentos e bebidas ad libitum. Os grupos foram os seguintes, conforme o alimento oferecido: Grupo controle -ração padrão e água; Grupo refrigerante calórico -ração padrão, refrigerante calórico e água; e Grupo refrigerante não calórico -ração padrão, refrigerante não calórico e água. Resultados: Não houve diferença estatística na ingestão total de energia, peso corporal e depósito adiposo entre os grupos. Entretanto, a ingestão de energia da ração foi 45% menor no Grupo refrigerante calórico comparado ao Grupo controle e ao Grupo refrigerante não calórico (198,7±0,7 kJ vs. 349,4±2,0 kJ e 373,0±1,3 kJ, respecti...

Highly Palatable and Hypercaloric Foods Chronic Intake Impair Food Control

“…This is considered one of the main contributors to the increase in the number of overweight and obese people 2,29,30 and abdominal adiposity 31 . Similar results were found in another study by our group, which analyzed the eff ects of caloric and non-caloric soft drink consumption during 17 weeks of treatment in rats 20 . A study on the food consumption in the Brazilian population, through a telephone survey, identifi ed an increase in caloric soft drink consumption from 60% in 2007 to 67% in 2009 32 .…”

“…In a previous study 20 , the supply of a balanced diet and caloric or non-caloric soft drinks did not cause changes in total energy intake, body weight, and intra-abdominal and perigonadal fat deposition in rats during the 17 weeks of exposure. However, caloric soft drink intake decreased the consumption of standard chow, with a consequent reduction in consumption of nutrients such as vitamins and minerals.…”

Highly palatable and hypercaloric chronic intake of food and soft drink leads to disruption in the normal dietary pattern in rats

“…This is considered one of the main contributors to the increase in the number of overweight and obese people [3,29,30] and abdominal adiposity [31]. Similar results were found in another study by our group, which analyzed the effects of caloric and non-caloric soft drink consumption during 17 weeks of treatment in rats [21]. A study on the food consumption in the Brazilian population, through a telephone survey, identi ed an increase in caloric soft drink consumption from 60% in 2007 to 67% in 2009 [32].…”

“…The cafeteria diet has been widely used as a model for inducing obesity in laboratory animals because of its great similarity with genesis and metabolic responses due to obesity in humans [18][19][20]. In a previous study [21], the supply of a balanced diet and caloric or non-caloric soft drinks did not cause changes in total energy intake, body weight, and intra-abdominal and perigonadal fat deposition in rats during the 17 weeks of exposure. However, caloric soft drink intake decreased the consumption of standard chow, with a consequent reduction in consumption of nutrients such as vitamins and minerals.…”