Construction of Prochloraz-Loaded Hollow Mesoporous Silica Nanoparticles Coated with Metal–Phenolic Networks for Precise Release and Improved Biosafety of Pesticides

Abstract

Currently, environmental-responsive pesticide delivery systems have become an essential way to improve the effective utilization of pesticides. In this paper, by using hollow mesoporous silica (HMS) as a nanocarrier and TA-Cu metal–phenolic networks as a capping agent, a pH-responsive controlled release nano-formulation loaded with prochloraz (Pro@HMS-TA-Cu) was constructed. The structure and properties of Pro@HMS-TA-Cu were adequately characterised and analysed. The results showed that the loading content of Pro@HMS-TA-Cu nanoparticles was about 17.7% and the Pro@HMS-TA-Cu nanoparticles exhibited significant pH-responsive properties. After a coating of the TA-Cu metal–phenolic network, the contact angle and adhesion work of Pro@HMS-TA-Cu nanoparticles on the surface of oilseed rape leaves after 360 s were 59.6° and 107.2 mJ·m−2, respectively, indicating that the prepared nanoparticles possessed excellent adhesion. In addition, the Pro@HMS-TA-Cu nanoparticles demonstrated better antifungal activity against Sclerotinia sclerotiorum and lower toxicity to zebrafish compared to prochloraz technical. Hence, the pH-responsive nanoparticles prepared with a TA-Cu metal–phenolic network as a capping agent are highly efficient and environmentally friendly, providing a new approach for the development of new pesticide delivery systems.

Degradable Self-Destructive Redox-Responsive System Based on Mesoporous Organosilica Nano-Vehicles for Smart Delivery of Fungicide

“…The peaks at 3434 and 1633 cm −1 were due to adsorbed water molecules or –OH groups on the surface of DMON nanoparticles. After loading prochloraz to the nanocarriers, two new peaks were displayed at 1698 and 1451 cm −1 , which were attributed to the stretching vibrations of C=O and C=N [ 55 , 56 ]. Next, the resultant hybrid nanoparticles were deposited with GA–Fe(III) complexes.…”

Effective control of the tomato wilt pathogen using TiO2 nanoparticles as a green nanopesticide

“…11 Nanocarriers such as mesoporous silica nanoparticles, coreshell ZnO@ZIF-8 nanospheres, and polysuccinimide were reported to be efficient nanopesticides that exhibited high stability and targeting properties, enhanced the adhesion to surfaces, and controlled the release of active ingredients. [12][13][14][15] Commonly, Ag-, Ti-, and Cu-based nanomaterials have been used as nanopesticides due to their antibacterial or insecticidal properties. 7 Nanoparticles combined with titanium dioxide, a metal oxide-TiO 2 NPs-have been regarded as an excellent antibacterial agent because of the unique photocatalytic performance.…”

Multifunctional Mesoporous Silica Nanosheets for Smart Pesticide Delivery and Enhancing Pesticide Deposition

“…Among them, mesoporous silica is widely employed in the delivery of nanopesticides because of its affordability, easy modification, large specific surface area, and favorable biocompatibility . For example, Shi et al prepared prochloraz-loaded hollow mesoporous silica nanocarriers coated with the TA-Cu metal-phenolic network, and this exhibited significant pH-responsive release and excellent adhesion . Zhou et al used zein-modified mesoporous silica as carriers to load avermectin, and this nanopesticide formulation displayed dual responsive release and improved wetting and adhesion properties .…”