Construction of microscale structures in enclosed microfluidic networks by using a magnetic beads based method

Wang, Zhenyu; Zhang, Xiaojuan; Yang, Jun; Yang, Zhongxue; Wan, Xiaoping; Hu, Ning; Zheng, Xiaolin

doi:10.1016/j.aca.2013.07.009

Cited by 6 publications

(3 citation statements)

References 19 publications

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“…Gold nanostructures were fabricated at defined positions within microchannels by electrochemical deposition, and used as electrocatalytic materials for glucose detection and suitable sensing surfaces for ultratrace arsenic (III) detection. Wang et al presented a magnetic-beads-based approach and built microstructures in enclosed microfluidic networks [41].…”

Section: Modification On Microchannelsmentioning

confidence: 99%

Recent progress in preparation and application of microfluidic chip electrophoresis

Cong

et al. 2015

J. Micromech. Microeng.

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Since its discovery in 1990, microfluidic chip electrophoresis (MCE) has allowed the development of applications with small size, fast analysis, low cost, high integration density and automatic level, which are easy to carry and have made commercialization efficient. MCE has been widely used in the areas of environmental protection, biochemistry, medicine and health, clinical testing, judicial expertise, food sanitation, pharmaceutical checking, drug testing, agrochemistry, biomedical engineering and life science. As one of the foremost fields in the research of capillary electrophoresis, MCE is the ultimate frontier to develop the miniaturized, integrated, automated all-in-one instruments needed in modern analytical chemistry. By adopting the advanced technologies of micro-machining, lasers and microelectronics, and the latest research achievements in analytical chemistry and biochemistry, the sampling, separation and detection systems of commonly used capillary electrophoresis are integrated with high densities onto glass, quartz, silicon or polymer wafers to form the MCE, which can finish the analysis of multi-step operations such as injection, enrichment, reaction, derivatization, separation, and collection of samples in a portable, efficient and super high speed manner. With reference to the different technological achievements in this area, the latest developments in MCE are reviewed in this article. The preparation mechanisms, surface modifications, and properties of different materials in MCE are compared, and the different sampling, separation and detection systems in MCE are summarized. The performance of MCE in analysis of fluorescent substance, metallic ion, sugar, medicine, nucleic acid, DNA, amino acid, polypeptide and protein is discussed, and the future direction of development is forecast.

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Section: Modification On Microchannelsmentioning

confidence: 99%

Recent progress in preparation and application of microfluidic chip electrophoresis

Cong

et al. 2015

J. Micromech. Microeng.

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“…However, it requires external energy such as electric fields and magnetic fields. Typical contactless trapping approaches include dielectrophoresis trapping [34,35], gel trapping [36], magnetic trapping [37,38], acoustic trapping [39,40] and laser trapping [41,42]. Specific cell trapping in microfluidic systems could be especially significant for separation methods which can cover many biological use, even larger that the item they selected such as bacteria cells and blood cells [43][44][45].…”

Section: Introductionmentioning

confidence: 99%

Recent Development of Microfluidic Technology for Cell Trapping in Single Cell Analysis: A Review

Deng

Guo

2020

Processes

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Microfluidic technology has emerged from the MEMS (Micro-Electro-Mechanical System)-technology as an important research field. During the last decade, various microfluidic technologies have been developed to open up a new era for biological studies. To understand the function of single cells, it is very important to monitor the dynamic behavior of a single cell in a living environment. Cell trapping in single cell analysis is urgently demanded There have been some review papers focusing on drug screen and cell analysis. However, cell trapping in single cell analysis has rarely been covered in the previous reviews. The present paper focuses on recent developments of cell trapping and highlights the mechanisms, governing equations and key parameters affecting the cell trapping efficiency by contact-based and contactless approach. The applications of the cell trapping method are discussed according to their basic research areas, such as biology and tissue engineering. Finally, the paper highlights the most promising cell trapping method for this research area.

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“…In many instances, they can be prepared from inexpensive materials, such as silicon, glass, polymethyl methacrylate, and polydimethylsiloxane, and mass-produced at a low cost; in fact, at a significantly lower cost than LOV platforms. However, microfluidic devices are usually dedicated; that is, they have a fixed architecture for predetermined chemistries and sample extraction protocols unless moving components (e.g., magnetic beads) are integrated into the microfluidic network [47]. The most severe limitation of microfluidic devices for real-life applications is the difficulty of handling complex matrices due to the ease of channel clogging or cross-contamination [48].…”

Section: Introduction: Perspective On Sample Preparationmentioning

confidence: 99%

Extraction for Analytical Scale Sample Preparation (IUPAC Technical Report)

2016

Chemistry International

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Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions? Contact the NRC Publications Archive team atPublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous. NRC Publications Record / Notice d'Archives des publications de CNRC:http://nparc.cisti-icist.nrc-cnrc.gc.ca/eng/view/object/?id=62582e82-c03f-4788-910b-85e44bea078f http://nparc.cisti-icist.nrc-cnrc.gc.ca/fra/voir/objet/?id=62582e82-c03f-4788-910b-85e44bea078fPure Appl. Chem. 2016; 88 (7) Abstract: Approaches for sample preparation are developing rapidly as new strategies are implemented to improve sample throughput and to minimize material and solvent use in laboratory methods and to develop on-site capabilities. In majority of cases the key step in sample preparation is extraction, typically used to separate and enrich compounds of interests from the matrix in the extraction phase. In this contribution, the topic of analytical scale extraction is put in perspective emphasising the fundamental aspects of the underlying processes discussing the similarities and differences between different approaches. Classification of extraction techniques according to the mass transfer principles is provided.

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Construction of microscale structures in enclosed microfluidic networks by using a magnetic beads based method

Cited by 6 publications

References 19 publications

Recent progress in preparation and application of microfluidic chip electrophoresis

Recent progress in preparation and application of microfluidic chip electrophoresis

Recent Development of Microfluidic Technology for Cell Trapping in Single Cell Analysis: A Review

Extraction for Analytical Scale Sample Preparation (IUPAC Technical Report)

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