Construction of Kevlar nanofiber/graphene oxide composite beads as safe, self-anticoagulant, and highly efficient hemoperfusion adsorbents

Yang, Yuliang; Yin, Shiqi; He, Chao; Wu, Xizheng; Yin, Jiarui; Zhang, Jue; Ma, Lang; Zhao, Weifeng; Cheng, Chong; Zhao, Changsheng

doi:10.1039/c9tb02789k

Cited by 26 publications

(19 citation statements)

References 55 publications

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“…3b). 142 Poly(aramid) nanofibres were utilized as a scaffold and combined to graphene oxide (GO). 136 First, poly(aramid) nanofibre -GO beads were produced by liquid-liquid phase separation.…”

Section: Materials Advances Reviewmentioning

confidence: 99%

Blood apheresis technologies – a critical review on challenges towards efficient blood separation and treatment

et al. 2021

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Section: Materials Advances Reviewmentioning

confidence: 99%

Blood apheresis technologies – a critical review on challenges towards efficient blood separation and treatment

et al. 2021

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“…Enzymatic nanoagents (EnzNA), which simulate the biocatalytic functions of natural enzymes, have overcome the natural enzymes' limitations and showed promising potential in combating pathogenic cells. [14][15][16] During the last few years, a large number of ROSbased EnzNAs have been constructed based on carbon, [17][18][19] organic molecules, [20] metal, [14,21,22] metal compounds, [23][24][25][26] and meta-organic framework (MOF). [27,28] Recently, transition-metal-based enzymatic nanoagents (TM-EnzNAs) have been intensively explored due to the special d-orbital electron of transition metal, [29][30][31][32][33][34] which become powerful nanoplatforms and exciting research frontiers in constructing nextgeneration nanotherapeutics to combat drug-resistant tumor and bacteria.…”

Section: Introductionmentioning

confidence: 99%

ROS‐Catalytic Transition‐Metal‐Based Enzymatic Nanoagents for Tumor and Bacterial Eradication

Cao

Xiang

et al. 2021

Adv Funct Materials

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The extensive research into developing new nanomedicines during the past few years has witnessed significant progress in diverse biomedical fields, especially for combating drug resistance in antitumor and antibacterial therapies. Recently, transition-metal-based enzymatic nanoagents (TM-EnzNAs) with catalytic production of reactive oxygen species (ROS) have been designed and intensively explored, which have become powerful nanoplatforms and exciting research frontiers in constructing next-generation nanotherapeutics to combat drug-resistant tumors and bacteria. Here, the focus is on the recent design, fundamental principles, and material chemistries in developing and applications of TM-EnzNAs. At first, the different ROS-producing mechanisms and the key factors to enhance ROS level are carefully concluded, and the analytic methods are systematically summarized. Then, the rationally engineered TM-EnzNAs via different synthetic approaches with high ROS producing efficiencies are comprehensively discussed, especially the catalytic activities, mechanisms, and structure-function relationships. After that, the representative applications of these ROS-catalytic TM-EnzNAs for antitumor and bacterial eradication are summarized in detail. Finally, the primary challenges and future perspectives have also been outlined. It is anticipated new therapeutic insights into combating drug-resistant tumors and bacteria will be provided, and significant new inspiration for designing future enzymatic nanoagents is offered.

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“…In recent years, research studies appeared ranging from membrane preparation, hemoperfusion adsorbents, and biomaterials. [37][38][39][40][41] Nanoscale bacterial cellulose (NBC), also called bacterial cellulose, is derived from aerobic bacterial like Acetobacter xylinum 42 and formed as an organic nanofiber. 43 It is one of the most versatile polymers, which is a homopolymer composed of β-D-glucopyranose units bonded by (1-4)-glycosidic linking.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of aramid nanoscale fiber‐based nanocomposite with transparency, flexibility, and selective adsorption capability

Wang

et al. 2021

Polymers for Advanced Techs

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Aramid nanofiber (ANF) has been regarded as an emerging excellent building block for preparing multifunctional high-performance composites, which are suitable for many applications in various fields. Based on this, for the first time, nanoscale bacterial cellulose (NBC) is used to modify ANF membrane via a direct blending followed with vacuum filtration. The chemical and physical structures of the NBC/ANF composite hybrid membranes (BAFM) are characterized by using Fourier transform infrared, X-ray diffraction, transmission electron microscope, and scanning electron microscope, demonstrating that NBC is well-dispersed into the ANF matrix. The two

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Construction of Kevlar nanofiber/graphene oxide composite beads as safe, self-anticoagulant, and highly efficient hemoperfusion adsorbents

Abstract: Brand new Kevlar/GO composite gel beads assembled by π–π interaction serve as safe and self-anticoagulant absorbents in hemoperfusion fields.

Cited by 26 publications

References 55 publications

Blood apheresis technologies – a critical review on challenges towards efficient blood separation and treatment

Blood apheresis technologies – a critical review on challenges towards efficient blood separation and treatment

ROS‐Catalytic Transition‐Metal‐Based Enzymatic Nanoagents for Tumor and Bacterial Eradication

Synthesis of aramid nanoscale fiber‐based nanocomposite with transparency, flexibility, and selective adsorption capability

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