Construction of Ergodic GMM-HMMs for Classification between Healthy Individuals and Patients Suffering from Pulmonary Disease

Abstract

Owing to the several cases wherein abnormal sounds, called adventitious sounds, are included in the lung sounds of a patient suffering from pulmonary disease, the objective of this study was to automatically detect abnormal sounds from auscultatory sounds. To this end, we expressed the acoustic features of the normal lung sounds of healthy people and abnormal lung sounds of patients using Gaussian mixture model (GMM)-hidden Markov models (HMMs), and distinguished between normal and abnormal lung sounds. In our previous study, we constructed left-to-right GMM-HMMs with a limited number of states. Because we expressed abnormal sounds that occur intermittently and repeatedly using limited states, the GMM-HMMs could not express the acoustic features of abnormal sounds. Furthermore, because the analysis frame length and intervals were long, the GMM-HMMs could not express the acoustic features of short time segments, such as heart sounds. Therefore, the classification rate of normal and abnormal respiration was low (86.60%). In this study, we propose the construction of ergodic GMM-HMMs with a repetitive structure for intermittent sounds. Furthermore, we considered a suitable frame length and frame interval to analyze acoustic features. Using the ergodic GMM-HMM, which can express the acoustic features of abnormal sounds and heart sounds that occur repeatedly in detail, the classification rate increased (89.34%). The results obtained in this study demonstrated the effectiveness of the proposed method.