Construction of Effective Nanosensor by Combining Semiconducting Polymer Dots with Diphenylcarbazide for Specific Recognition of Trace Cr (VI) Ion in Water and Vitro

Abstract

Hexavalent chromium (Cr (VI)) ion, as highly toxic environmental pollution, severely endangers the ecological environment and public health. Herein, a fluorescent nanosensor (PFO-DPC) was constructed by combining semiconducting polymer dots with diphenylcarbazide (DPC) for sensing Cr (VI) ion in aqueous solution and living cells. DPC and poly (styrene-co-maleic anhydride) (PSMA) polymer mixed with polyfluorene (PFO) were utilized for selectively indicating Cr (VI) ion and improving the efficiency of detection, respectively. The presence of Cr (VI) ion effectively turned off the blue and green fluorescence of PFO-DPC in the aqueous environment, and the fluorescence quenching efficiency exhibited a good linear relationship between the range of 0.0 to 2.31 nM (R2 = 0.983) with a limit of detection (LOD) of 0.16 nM. The mechanism of fluorescence quenching could possibly be attributed to the internal filtration effect (IFE). Additionally, PFO-DPC showed a satisfactory performance in monitoring intracellular Cr (VI) ion. Our results indicate that the sensor is promising in various applications.

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

“… Antibacterial [ 144 ] 71 PFO-BODIPY 375 520/680 34/16 Cell Tracking [ 145 ] 72 PFO-DPC 380∼400 440/470 N.A. Chromium ion detection [ 146 ] 73 PFODTBT 200 N.A. N.A.…”

Recent advancements in nano sensors for air and water pollution control

“…Greenly synthesized carbon dots from microalgae biomass biochar Cr 6+ Pena et al 14 Carbon dots synthesized from Poria cocos polysaccharide Cr 6+ Huang et al 145 diphenylcarbazide (DPC) combined with Semiconducting polymer dots-based fluorescence nanosensor Cr 6+ Dou et al 146 Fe 3 O 4 @Pectin-polymethacrylimide@graphene quantum dot Cr 3+ Barzegarzadeh et al 147 Schiff base immobilized mesoporous SBA-15 silica Cu 2+ Zhang et al 148 Bis-Schiff base functionalized Fe 3 O 4 nanoparticles Cu 2+ Zhu et al 149 Quaternized salicylaldehyde Schiff base side-chain polymer grafted magnetic Fe 3 O 4 nanoparticles (Fe 3 O 4 @SiO 2 -PAP)…”