Construction of dental pulp decellularized matrix by cyclic lavation combined with mechanical stirring and its proteomic analysis
Zhijun Zhang,
Fei Bi,
Yibing Huang
et al.
Abstract:The decellularized matrixhas a great potential for tissue remodeling and regeneration; however, decellularization could induce host immune rejection due to incomplete cell removal or detergent residues, thereby posing significant challenges for its clinical application. Therefore, the selection of an appropriate detergent concentration, further optimization of tissue decellularization technique, increased of biosafety in decellularized tissues, and reduction of tissue damage during the decellularization proce… Show more
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