Construction of a Prognostic DNA Damage Repair Gene-related LncRNA Signature by Integrated Analysis of Bulk- and Single-cell RNA Sequencing Data in Lung Adenocarcinoma
Abstract:Despite the development of technology, the prognosis of patients with lung adenocarcinoma (LUAD) has not improved. Therefore, we sought to investigate the potential clinical utility of a risk prognosis model in prognostic stratification. For this purpose, DNA damage repair gene-related (DDRG-related) long noncoding RNAs (lncRNAs) were screened based on a single-cell RNA transcriptome to construct such a model. A total of 510 LUAD samples were selected from The Cancer Genome Atlas-LUAD (TCGA-LUAD) dataset. Samp… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.