Construction and validation of a nomogram for hepatocellular carcinoma patients treated by traditional Chinese medicine based on inflammation, nutrition, and blood lipid indicators

Yu, Xiaopeng; Yang, Renyi; He, Ziqi; Zeng, Puhua

doi:10.1007/s00432-023-04830-y

Cited by 2 publications

(5 citation statements)

References 40 publications

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“… 19 TCM nutritional therapy starts with the patient’s kidney, liver, and heart, achieving the principle of treating the root cause of the disease. 8 , 9 According to the nutrition principle of TCM, food materials should be selected reasonably to assist the use of herbs for nourishing the kidney and liver, increase the body autoregulation and compensatory effect, and improve the overall physical condition of the patient. 23 The nutrition in the TCM preparation of the current study have the effect of nourishing kidneys, liver and activating blood circulation.…”

Section: Discussionmentioning

confidence: 99%

“…5,6 In terms of treatment, the main approach should be, therefore, to warm the spleen and tonify the kidney, while also using methods such as dispelling phlegm, soothing the liver, and resolving blood stasis. [7][8][9] TCM nutrition is a fusion of physiology and pathology under the guidance of basic theories of TCM. This innovative dietary therapy and auxiliary medical method organically combines dialectical diet with modern nutrition.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…This innovative dietary therapy and auxiliary medical method organically combines dialectical diet with modern nutrition. 8 , 9 There are currently no literature reports on the treatment of overweight PCOS patients using TCM nutrition. Therefore, this study retrospectively analyzes the clinical efficacy of TCM nutrition treatment in overweight patients with PCOS to provide reference for future clinical interventions.…”

Section: Introductionmentioning

confidence: 99%

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The effect of Bushenhuoxue nutritional decoction in the treatment of overweight patients with polycystic ovarian syndrome

Fu,

Chen,

Huang

et al. 2024

Pak J Med Sci

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Objective: To assess the effect of Traditional Chinese Medicine (TCM) nutrition treatment (Bushenhuoxue nutritional decoction) in overweight patients with polycystic ovary syndrome (PCOS). Methods: Retrospective analysis of 96 overweight patients with PCOS who received treatment in our hospital from October 2020 to June 2022 was done. Among them, 46 patients received routine drug treatment and daily dietary intervention (control group), while 50 patients received additional TCM nutrition support in addition to routine treatment (observation group). Glucose and lipid metabolism indicators and hormone levels were compared between the two groups before and after the treatment. Ovulation rate, pregnancy rate, and adverse reactions were compared between both groups one year after the treatment. Results: After treatment, the improvement of glucose and lipid metabolism indicators and hormone levels in the observation group was significantly better than in the control group (P<0.05). After treatment, the TCM syndrome scores of the two groups were lower than that before treatment (P < 0.001), and the TCM syndrome scores of the observation group was lower than that of the control group (P < 0.001).Ovulation and pregnancy rates were significantly higher in the observation group compared to the control group at 1-year follow up (P<0.05), and the incidence of adverse reactions in the observation group was significantly lower than that in the control group (P<0.05). Conclusions: Combined with conventional drug treatment, TCM nutrition treatment can significantly improve glucose and lipid metabolism, hormone levels, and TCM syndrome of overweight PCOS patients, increase the ovulation and pregnancy rates, and reduce potential adverse reactions. doi: https://doi.org/10.12669/pjms.40.6.9304 How to cite this: Fu J, Chen Y, Huang Z, Wang X. The effect of Bushenhuoxue nutritional decoction in the treatment of overweight patients with polycystic ovarian syndrome. Pak J Med Sci. 2024;40(6):1105-1110. doi: https://doi.org/10.12669/pjms.40.6.9304 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The effect of Bushenhuoxue nutritional decoction in the treatment of overweight patients with polycystic ovarian syndrome

Fu,

Chen,

Huang

et al. 2024

Pak J Med Sci

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“…As the paramount subtype of liver cancer, HCC accounts for an astounding 75% to 90% of all primary liver malignancies, casting a grim foreboding on patient prognosis. 3 Notably, it is noteworthy to mention that HCC exhibits a higher incidence in males compared to females. 4 Regrettably, the overall 5-year survival rate is less than 15%, with late-stage patients observing a precipitous dip to a mere 10.1%.…”

Section: Introductionmentioning

confidence: 99%

The Curative and Preventative Effects of Traditional Chinese Medicine on Ferroptosis of Hepatocellular Carcinoma

Peng,

Yang,

et al. 2023

Natural Product Communications

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Primary hepatocellular carcinoma (HCC), a leading variant of primary liver cancer, holds significant global prevalence with strong implications for morbidity, mortality, and prognosis. Prevention and treatment paradigms are perpetually evolving in response to this malignancy. Ferroptosis, an iron and reactive oxygen species (ROS) dependant mode of cellular death, is catalyzed by an overabundance of lipid peroxidation, subsequently causing plasma membrane rupture. There is a unique interest in the relationship of ferroptosis with HCC development and progression, as compared to the interplay of apoptosis, autophagy, and necroptosis. Recent discoveries underscore the implications of ferroptosis in HCC evolution. Moreover, Traditional Chinese Medicine (TCM) and its respective active components display anti-HCC properties, a mechanism thought to be primarily attributed to the induction of ferroptosis in HCC cells. In support of preventive and therapeutic strategies for HCC, this manuscript provides a comprehensive review of the role of ferroptosis in HCC, its regulatory network, and the cutting-edge research focused on the treatment of HCC via ferroptosis modulation using TCM.

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Construction and validation of a nomogram for hepatocellular carcinoma patients treated by traditional Chinese medicine based on inflammation, nutrition, and blood lipid indicators

Cited by 2 publications

References 40 publications

The effect of Bushenhuoxue nutritional decoction in the treatment of overweight patients with polycystic ovarian syndrome

The effect of Bushenhuoxue nutritional decoction in the treatment of overweight patients with polycystic ovarian syndrome

The Curative and Preventative Effects of Traditional Chinese Medicine on Ferroptosis of Hepatocellular Carcinoma

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