Abstract. For certain kinds of 3-manifolds, the question whether such a manifold can be obtained by nontrivial Dehn surgery on a knot in S3 is reduced to the corresponding question for hyperbolic knots. Examples are, whether one can obtain S3, a fake S3, a fake S3 with nonzero Rohlin invariant, S1 X S1, a fake S] X S2, S] X S2 # M with M nonsimply-connected, or a fake lens space.1. Introduction and statement of results. In the present paper we show that for certain kinds of 3-manifolds, the question whether such a manifold can be obtained by nontrivial Dehn surgery on a knot reduces to the corresponding question for simple knots. By Thurston's uniformization theorem for Haken manifolds [27], a knot is simple if and only if it is either hyperbolic (i.e. its complement possesses a complete hyperbolic structure with finite volume), or a torus knot. Since the manifolds obtained by Dehn surgery on the latter can be completely described (see [20], and §7), we essentially have a reduction to the case of hyperbolic knots.If Kis an (unoriented) knot in (oriented) S3, and r = m/n G Q L) {oo}, (m, n) = I, let (K; r) denote the closed, oriented 3-manifold obtained by Dehn surgery of type r on K. (We use the terminology of [21, pp. 258-259]; see §2.) The unknot is denoted by O, so that (O; r) is the lens space L(m, n), if | m \¥= 0,1, or S3 = (O; l/n), or S1 X S2 -(O;0). The manifolds to which our arguments apply are those that are atoroidal, that is, contain no imcompressible torus. Our main result may then be stated as follows. (Throughout, all 3-manifolds are oriented, ~ denotes orientation-preserving homeomorphism, and # connected sum.)