Construcao do Estudo Longitudinal de Saude do Adulto (ELSA-Brasil)

Lotufo, Paulo A.

doi:10.1590/s0034-8910.2013047s20002

Cited by 35 publications

(7 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The baseline data was collected from 2008 to 2010 in public universities and research institutions in six Brazilian capitals: the Universidade Federal da Bahia (UFBA), Universidade Federal de Minas Gerais (UFMG), Centro Federal de Educação Tecnológica de Minas Gerais (CEFET-MG), Universidade Federal do Espírito Santo (UFES), Fundação Oswaldo Cruz (FIOCRUZ), Universidade de São Paulo (USP) and Universidade Federal do Rio Grande do Sul (UFRGS). The purpose of the ELSA-Brasil study was to investigate the risk factors and incidence of chronic diseases, especially diabetes and cardiovascular diseases 15 . The data collection was performed via face-to-face interviews, anthropometric measures, arterial pressure and laboratorial tests in the six research centres 16 .…”

Section: Methodsmentioning

confidence: 99%

“…Samples were collected after a 12-hour fast, stored in a freezer at −80 °C and sent to the certified central laboratory in São Paulo. An oral glucose tolerance test (OGTT) was administered to all participants without a known diabetes diagnosis [15]. Glycaemia was measured using the enzymatic colorimetric method (ADVIA 1200 Siemens Deerfield, IL, USA), and glycated haemoglobin A1c was measured using high-pressure chromatography (HPLC -Bio-Rad Laboratories, Hercules, CA, USA).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil)

Teixeira

Passos

Barreto

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Diabetes has been associated with cognitive changes and an increased risk of vascular dementia andAlzheimer's disease, but it is unclear whether there are associations between diabetes and early alterations in cognitive performance. The present study consisted of a cross-section analysis of 14,444 participants aged 35-74 years and from a developing country at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil); these participants were recruited between 2008 and 2010. We investigated whether there was an association between diabetes and early changes in the cognitive performance of this Brazilian population. To assess cognitive domains, we used the word-list learning, word-list delayed recall and word recognition tests along. Phonemic verbal fluency tests included semantic phonemic test (animals) and a phonemic test (words beginning with the letter f). executive functions associated with attention, concentration and psychomotor speed were evaluated using the Trail Making Test B. The exposure variable in the study was defined as diabetes. Multiple linear regression was used to estimate the association between diabetes and cognitive performance. the results were adjusted for age, sex, education, hypertension, coronary disease, depression, physical activity, smoking, alcohol consumption, and the cholesterol/HDL-C ratio. We found a significant association between diabetes and decreased memory, language and executive function (attention, concentration and psychomotor speed) performance in this population from a country with a distinct epidemiological profile, even after adjusting for the main intervening variables.The world population is ageing, and the incidence of neurodegenerative diseases associated with age is increasing. Diabetes mellitus (diabetes) has been associated with cognitive changes and an increased risk of vascular dementia 1 and Alzheimer's disease 2 . The number of people diagnosed with diabetes worldwide is approximately 422 million individuals 3 . Cognitive dysfunction in individuals with diabetes can result from interactions between inherent metabolic abnormalities, such as hyperglycaemia, hyperinsulinaemia, and micro-and macrovascular complications, in addition to hypertension, dyslipidaemia, depression and obesity 4-7 . The precise mechanisms involved in degenerative diseases in patients with diabetes are unknown and not fully understood; thus, they are considered quite complex and dynamic 8 .Some studies show a worse performance in cognitive tests among patients with diabetes than among individuals without diabetes, with deficits in several domains, especially executive function, memory, psychomotor speed and attention 9,10 . A systematic review that included case-control and population-based studies showed that the risk of overall cognitive dysfunction was increased in people with diabetes in five of seven cohorts. In addition, the association of decreased cognitive performance in one or more domains in was reported in 13 of the 20 cross-sectional studies and in five of t...

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil)

Teixeira

Passos

Barreto

et al. 2020

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Sobre fomento científico, esta revisão deixa patente a baixa disponibilidade de estudos específicos na literatura brasileira, um agudo contraste com a alta relevância e demanda de uma política prioritária que se aproxima de duas décadas de vultosos investimentos. Estudos futuros podem se beneficiar dos condicionantes e indicadores das redes exitosas no país, das quais podem ser citados os estudos 'ELSA Brasil' 46,47 ; 'ELSI Brasil' 48 ; e 'ÉRICA' 49 . Mesmo configurada como 'rede de serviços', o peso científico e tecnológico de que dispõe a Rebrats a torna caso compulsório.…”

Section: Conclusõesunclassified

Fatores condicionantes na conformação e desempenho das redes de pesquisa fomentadas pelo Ministério da Saúde com foco em saúde coletiva

Mello

Tenorio

Uchimura

2020

Rev Eletron Comun Inf Inov Saúde

View full text Add to dashboard Cite

Este artigo apresenta uma análise integrada de três estudos de caso sobre fomentos de redes de pesquisa instituídas pelo Departamento de Ciência e Tecnologia do Ministério da Saúde (Decit), envolvendo três grandes áreas de interesse estratégico nacional: pesquisa clínica, doenças negligenciadas e saúde coletiva. Com foco na saúde coletiva, o estudo desenvolvido, estimulado pelo insucesso do fomento da Rede Nacional de Pesquisas sobre Política de Saúde (RNPPS), busca fundamentar condicionantes que difiultam ou promovem a consolidação de redes de pesquisa nessa área. A capacidade de construção das chamadas, relacionada ao grau de maturidade do campo disciplinar, o modelo de gestão de redes complexas, e o perfi de liderança estão entre os principais condicionantes observados. A par de desafis comuns na consolidação de redes de pesquisa, a saúde coletiva deve aprender a equilibrar com maior propriedade os pesos político e científio na balança do seu campo disciplinar.

show abstract

“…In ELSA-Brazil, the recruitment of participants and interviews, clinical exams and the collection, processing, storage and transfer of biological samples toke place in the six research centers 34 . In addition, all interviews, measurement taking and laboratory testing were performed by trained, certified teams, and all procedures were subject to quality control 35 .…”

Section: Data Collection and Processingmentioning

confidence: 99%

Association between perceived racial discrimination and hypertension: findings from the ELSA-Brasil study

et al. 2018

View full text Add to dashboard Cite

show abstract

Construcao do Estudo Longitudinal de Saude do Adulto (ELSA-Brasil)

Cited by 35 publications

References 20 publications

Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil)

Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil)

Fatores condicionantes na conformação e desempenho das redes de pesquisa fomentadas pelo Ministério da Saúde com foco em saúde coletiva

Association between perceived racial discrimination and hypertension: findings from the ELSA-Brasil study

Contact Info

Product

Resources

About