Abstract:We have previously shown that basic fibroblast growth factor (bFGF) stimulates megakaryocytopoiesis and granulopoiesis in vitro and that normal haematopoietic cells and several leukaemic cell lines express FGF receptors. In this paper, we demonstrate by reverse transcriptase‐mediated polymerase chain reaction (RT‐PCR) that bFGF mRNA is expressed in two leukaemia cell lines with megakaryocyte features (Meg‐01 and K562), in two lymphocytic cell lines (Hut 78 and CA) and in normal human peripheral blood mononucle… Show more
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