2024
DOI: 10.5187/jast.2023.e93
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Constipation anti-aging effects by dairy-based lactic acid bacteria

Mohamad Hafis Jaafar,
Pei Xu,
Uma-Mageswary Mageswaran
et al.

Abstract: Constipation, which refers to difficulties in defecation and infrequent bowel movement in emptying the gastrointestinal system that ultimately produces hardened fecal matters, is a health concern in livestock and aging animals. The present study aimed to evaluate the potential effects of dairy-isolated lactic acid bacteria (LAB) strains to alleviate constipation as an alternative therapeutic intervention for constipation treatment in the aging model. Rats were aged via daily subcutaneous injection of D-galacto… Show more

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Cited by 4 publications
(2 citation statements)
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“…Many of these amino acids can participate in several metabolic pathways involving amino acids, carbohydrates, and nucleotides [69,70]. Threonine could stand out among the amino acids detected at 48 h of fermentation because it is essential in maintaining mucosal integrity and barrier function by supporting mucin secretion [71].…”
Section: Discussionmentioning
confidence: 99%
“…Many of these amino acids can participate in several metabolic pathways involving amino acids, carbohydrates, and nucleotides [69,70]. Threonine could stand out among the amino acids detected at 48 h of fermentation because it is essential in maintaining mucosal integrity and barrier function by supporting mucin secretion [71].…”
Section: Discussionmentioning
confidence: 99%
“…2,7 Probiotics are live microbiota that provide health benefits to the host by maintaining the homeostasis of the intestinal microbiota and the immune system and possessing antiinflammatory and anti-aging properties in human and animal. [8][9][10][11][12][13][14][15][16][17][18] Recent studies have shown that Lacticaseibacillus rhamnosus species are probiotics, a type of intestinal bacteria, and have been reported to provide various biological activi-ties: 19 anti-inflammatory, 20 anti-obesity, 21 immune modulation, 22 gut health (IBD and IBS), [23][24][25] and cholesterol level reduction. In addition, the Lacticaseibacillus rhamnosus IDCC3201 strain used in our study was isolated from infant feces, and it has been confirmed to be 18 anti-allergic, 26 antiinflammatory, anti-pathogenic, 19 and immunomodulatory.…”
Section: Introductionmentioning
confidence: 99%