“…Time-domain and hybrid models entail time domain signal processing within the brain. Anatomical and physiological specializations to support such processing include transduction and coding of acoustic temporal structure in the auditory nerve (up to 4-5 kHz or possibly higher, Heinz et al, 2001;Hartmann et al, 2019;Carcagno et al, 2019;Verschooten, 2019), specialized synapses in the cochlear nucleus and subsequent relays, and fast excitatory and inhibitory interaction in the medial and lateral superior olives (MSO and LSO) (Grothe, 2000;Zheng and Escabí, 2013;Keine et al, 2016;Beiderbeck et al, 2018;Stasiak et al, 2018) and other nuclei (Albrecht et al, 2014;Caspari et al, 2015;Felix et al, 2017). Some of these circuits are interpreted as serving binaural interaction but could be borrowed for other needs (see Joris and van der Heijden, 2019;Kandler et al, 2020, for recent reviews).…”